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Brain Cancer

A brain slice with glioblastoma multiforme

·June 13, 2013·3 min read

Metabolic Molecule Drives Growth Of Aggressive Brain Cancer

Researchers have identified an abnormal metabolic pathway which drives cancer cell growth in particular glioblastoma brain cancer subtypes.

The image shows an MRI scan of a patient with brain cancer. The tumor is highlighted in blue.

Brain Cancer Featured

·May 14, 2013·4 min read

New Drug Enhances Radiation Treatment for Brain Cancer in Preclinical Studies

A new drug could help increase the effectiveness of radiation therapy for patients with glioblastoma multiforme, the most deadly form of brain cancer. The ATM kinase inhibitor, in combination with radiation therapy, helped significantly extend survival rates in mouse models of GBM.

The diagram shows how adrenocorticotropin hormone is secreted in Cushing's disease.

Featured Genetics

·May 7, 2013·3 min read

Scientists Find Potential Therapeutic Target for Cushing’s Disease

Researchers have identified that the TR4 protein, which regulates a gene that produces ACTH, drives the formation of pituitary tumors in Cushing's disease.

The image is a brain scan of a patient with recurrent glioblastoma.

Brain Cancer Featured

·March 12, 2013·3 min read

Using Fat to Fight Brain Cancer

Researchers discover stem cells from a patient's own fat could potentially deliver new treatments directly to the brain after the removal of a glioblastoma, the most common form of brain cancer.

The image appears to show the L3MBTL3 protein. The caption best describes the image.

Brain Cancer Featured

·March 1, 2013·3 min read

New Chemical Probe Provides Tool to Investigate Role of Malignant Brain Tumor Domains

Researchers announce the discovery of a chemical probe, UNC1215, which could be used to investigate the function of malignant brain tumor domain proteins.

The image shows an MRI scan of a glioblastoma multiforme in a human brain.

Brain Cancer Featured

·February 26, 2013·3 min read

Novel Combination Therapy Shuts Down Escape Route, Killing Glioblastoma Tumor Cells

A new study discovers molecular pathways that could lead to new targeted therapies which may potentially treat Glioblastoma, the most common and lethal form of brain cancer in adults.

The image shows a chalk outline of a human head surrounded by question marks.

Brain Cancer Featured

·February 21, 2013·2 min read

Neuroscientist Sheds Light on Cause for ‘Chemo Brain’

A new study argues that prolonged chemotherapy decreases the development of new brain cells, and disrupts ongoing brain rhythms in the part of the brain responsible for making new memories.

The image shows a section of mouse liver showing an apoptotic cell.

Electrophysiology Featured

·February 2, 2013·3 min read

Caught in the Act: Researchers Capture Key Moments in Cell Death

Researchers visualize the molecular changes in a critical cell death protein that force cells to die. Defects in cell death have been linked to the development of diseases such as cancer and neurodegenerative conditions.

The image shows a microscopic view of a typical neuroblastoma with rosette formation.

Brain Cancer Featured

·January 29, 2013·2 min read

Dendritic Cell Vaccine for Relapsed Neuroblastoma Patient Induces Complete Remission

Cancer treatment vaccine research leads to remission in a child with a relapsed neuroblastoma.

The image shows scans of brains with tumors.

Brain Cancer Featured

·January 25, 2013·3 min read

Genetic Landscape of Common Brain Tumors Holds Key to Personalized Treatment

Researchers discover the genetic landscape of the most common form of brain tumor can be explained by abnormalities in five genes. The finding could help to develop personalized medical therapies and treatment options.

Brain Cancer Featured

·January 17, 2013·3 min read

Researchers Identify Enzyme Involved in Deadly Brain Tumors

In a study published in Neuro-Oncology, researchers at Mayo Clinic identify an important association between the naturally occurring enzyme Kallikrein 6, also known as KLK6, and glioblastoma multiforme tumors.

Neurons are shown. Caption describes it well.

Brain Cancer Featured Neurology

·October 22, 2012·3 min read

Aggressive Brain Tumors Can Originate from a Range of Nervous System Cells

Scientists have long believed that glioblastoma multiforme, the most aggressive type of primary brain tumor, begins in glial cells that make up supportive tissue in the brain or in neural stem cells. Researchers found that the tumors can originate from other types of differentiated cells in the nervous system, including cortical neurons.