Researchers identified specific receptors for acetylcholine that reroute information flow through memory circuits in the hippocampus. The findings could have implications for the development of drugs to help enhance or protect memory from diseases associated with cognitive decline.
A new study finds dopamine increases responses to stressful stimuli, not just pleasurable ones. The findings could have implications for the treatment of mental health disorders and addiction.
Stem cell study reveals astrocytes carrying the Alzheimer's associated APOE4 gene release more cholesterol than those carrying the APOE3 gene. Findings shed light on how different versions of the APOE gene in astrocytes influence amyloid-beta production and how the oversupply of cholesterol associated with APOE4 astrocytes may promote amyloid-beta formation in Alzheimer's patients.
Amyloid-beta proteins created in the liver are carried in the blood by lipoproteins to the brain. This results in neurodegeneration, brain atrophy, and inflammation, which are common features of Alzheimer's disease.
A new deep learning algorithm identified key features underlying success in the art world. Researchers report a link between exploration and exploitation was associated with artistic success.
Researchers discovered mutations of the OPTN gene resulted in increased herpesvirus 1 growth in the brains of mice, leading to the death of local neurons. This resulted in accelerated neurodegeneration. OPTN deficiency was also associated with impairments in immune response. While these findings are specific to the HSV-1 virus, researchers believe the findings may apply to up to eight herpesvirus infections.
Older adults who frequently connect with friends and others in social situations perform better on cognitive function tests than those who are not so social.
A new, open access repository incorporates frequently asked questions and answers by genomics researchers to provide a better general understanding of what their studies do, and do not show.
Study reports a significant number of people with Parkinson's disease have precise deficits when learning from instructions. Researchers say the problems are associated with differences in brain function.