Researchers end decade-long search for mechanical pain sensor
Researchers have that discovered a protein in the membrane of sensory neurons is involved in our capacity to experience mechanical pain.... Read More...
pain
First treatment for pain using human stem cells a success
Transplanting GABAergic cells derived from human-induced pluripotent stem cells into mice resulted in safe, lasting, and effective relief from extreme neuropathic pain. Researchers hope to begin human testing within five years.... Read More...
One in three pain patients suffer side effects after ketamine infusion therapy
35% of patients who used ketamine to manage pain reported significant side effects ranging from hallucination, out-of-body experiences, visual disturbances, and urinary dysfunction. 20% of the side effects were linked directly to ketamine, and 15% associated with ketamine in combination with other drugs.... Read More...
Brain mechanisms have potential to block arthritis pain
Researchers discover the amygdala is a critical site of action for pain modulation. An existing compound, LY379268, provides pain-relieving effects and helps to reduce anxiety.... Read More...
Molecular link between chronic pain and depression revealed
Inhibitory inputs to the neural circuit between the dorsolateral bed nucleus of the stria terminalis (dlBNST) to the ventral tegmental area (VTA) increase when a person is in chronic pain. This alteration is mediated by enhanced corticotropin-releasing factor signaling within the dlBNST, leading to suppression of the mesolimbic dopaminergic system. The result is depressive mood and anhedonia associated with chronic pain.... Read More...
Does migraine leave your head spinning? Noninvasive treatment shows early promise
Noninvasive vagus nerve stimulation (nVNS) helps improve symptoms of pain and vertigo in patients with vestibular migraines.... Read More...
Persistent headache or back pain ‘twice as likely’ in the presence of the other
Researchers have identified a positive association between persistent lower back pain and headache disorders. The study reveals those with persistent back pain or persistent headache disorders are twice as likely to suffer from both disorders at the same time.... Read More...
Migraine sufferers needlessly enduring agonizing pain
Many people who suffer migraines are often diagnosed with other conditions. For those with a clinical diagnosis, many are unaware of treatment options available for pain and to slow the frequency of attacks.... Read More...
Scorpion toxin that targets ‘wasabi receptor’ may help solve mystery of chronic pain
WaTx, a short protein in the venom of Australian Black Rock scorpions, is helping researchers uncover new information about chronic pain and inflammation. ... Read More...
Cannabis flower is an effective mid-level analgesic medication for pain
People who used while dried cannabis flowers or cannabis with higher levels of THC had the greatest analgesic response to pain. Those who used CBD reported lower levels of pain relief.... Read More...
New pain organ discovered in the skin
In a groundbreaking finding, researchers have identified a new sensory organ under the skin that can detect pain as a result of impact or pinpricks. The organ comprises of glial cells with multiple long protrusions which collectively make up the mesh-like organ under the skin.... Read More...
Adults who mix cannabis with opioids for pain report higher anxiety and depression
Compared to opioid use alone, co-use of cannabis and opioids to treat pain is associated with increased anxiety and depression symptoms in adults.... Read More...