FeaturedNeurologyNeuroscienceOpen Neuroscience Articles·May 30, 2020New gut-brain link: How gut mucus could help treat brain disordersChanges in gut mucus may contribute to Alzheimer's, Parkinson's, and other neurological disorders. Researchers noted changes in types of gut mucus bacteria in those with a range of neurological disorders compared to their healthy peers. Findings suggest those with reduced gut mucus protection may be more susceptible to gastrointestinal problems. Read More
FeaturedNeurologyNeuroscienceOpen Neuroscience Articles·May 29, 2020How toxic protein spreads in Alzheimer’s diseaseTau spreads through the human brain via neural communication pathways. The spread is accelerated by the presence of amyloid-beta. Read More
FeaturedGeneticsNeuroscienceOpen Neuroscience Articles·May 26, 2020Dementia gene raises risk of severe COVID-19People with the Alzheimer's associated ApoE e4e4 gene have increased vulnerability to developing severe symptoms of COVID-19 if they become infected with the virus. Findings suggest those with the dementia-related gene have double the risk of developing severe coronavirus symptoms compared to those who those with the common e3e3 form of the APOE gene. Read More
FeaturedNeurologyNeuroscience·May 21, 2020Exercise improves memory and boosts blood flow to brainFollowing a one year program of aerobic exercise improves memory function and boosts blood flow to brain areas critical for cognition in older adults with risk factors for dementia. Read More
FeaturedNeurologyNeuroscienceOpen Neuroscience Articles·May 16, 2020Certain Memory Complaints Predict Future DementiaSubjective cognitive complaints may be the earliest detectable stages of preclinical dementia. Read More
FeaturedNeurologyNeuroscienceOpen Neuroscience Articles·May 14, 2020Retinal texture could provide early biomarker of Alzheimer’s diseaseThe topmost layer of neurons in the retina of mouse models of Alzheimer's disease exhibits textural changes. The findings could be a new biomarker for Alzheimer's disease. Read More
FeaturedNeurologyNeuroscience·May 11, 20203D brain-like tissue model links Alzheimer’s disease with herpesA 3D human tissue culture model demonstrated a possible causal relationship between Alzheimer's disease and herpes simplex virus 1 (HSV-1) infection. 40 Alzheimer's associated genes were over-expressed in the HSV-1 infected brain tissue, including genes associated with the production of amyloid-beta. Read More
FeaturedNeurologyNeuroscience·May 5, 2020New evidence that higher caffeine and urate levels are protective against Parkinson’sCaffeine and urate have been associated with a reduced risk of idiopathic Parkinson's disease. Researchers noted a lower caffeine intake in idiopathic Parkinson's patients. Increasing caffeine consumption was linked to decreased odds of being diagnosed with Parkinson's. Lower levels of blood urate were also associated with an increased risk of Parkinson's disease. Read More
FeaturedNeurologyNeuroscienceOpen Neuroscience Articles·May 5, 2020Flavonoid-rich berries, fruits and tea may have a protective benefit against Alzheimer’sConsuming a flavonoid-rich diet could help combat the development and progression of Alzheimer's disease for those with risk factors. Low intake of specific flavonoids, especially anthocyanins, which are found in blueberries and strawberries, was associated with a four-fold risk of developing Alzheimer's. Read More
artificial intelligencedeep learningFeaturedmachine learningNeurologyNeuroscienceneurotechOpen Neuroscience Articles·May 4, 2020Artificial intelligence algorithm can accurately predict risk and diagnose Alzheimer’s diseaseCombining brain imaging data with a new machine learning algorithm, researchers can accurately predict the risk and determine a diagnosis for Alzheimer's disease. Read More
FeaturedNeurologyNeuroscienceneurotechOpen Neuroscience Articles·April 30, 2020Nanodevices for the brain could thwart formation of Alzheimer’s plaquesResearchers have developed a new approach to prevent amyloid plaque formation by engineering a nanodevice that captures the peptides before they can assemble. The silica nanodevice might be a new tool in the treatment and prevention of Alzheimer's disease and other neurodegenerative diseases associated with amyloid-beta. Read More
FeaturedGeneticsNeurologyNeuroscience·April 29, 2020APOE4 triggers early breakdowns in the blood-brain barrierAPOE4, a gene implicated as a risk factor for Alzheimer's disease, triggers leaks in the blood-brain barrier. The damage to capillaries APOE4 causes correlates with increased levels of cyclophilin, a protein that causes the inflammation that is a signature of early Alzheimer's. Read More
