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Alzheimer’s disease

This shows a man, a brain, and blood vials.

·July 14, 2025·6 min read

Middle-Age Clues: Blood Biomarkers Signal Alzheimer’s Risk Early

New research shows that signs of Alzheimer’s disease can already be detected in the blood of people as young as their 40s. Finnish scientists found elevated Alzheimer’s-related biomarkers in middle-aged adults, especially among those with maternal history or kidney disease.

Featured Neurology Neuroscience

·July 14, 2025·8 min read

Why Women Face Higher Alzheimer’s Risk

Women are nearly twice as likely as men to develop Alzheimer’s disease, a disparity that can’t be fully explained by longevity alone. Researchers are exploring biological differences, focusing on X chromosome-linked genes and hormonal shifts like menopause.

Featured Genetics Neurology Neuroscience

·July 9, 2025·7 min read

Genes and Brain Wiring Team Up in Alzheimer’s Spread

A new study reveals how genes influence where and how Alzheimer’s-related tau protein spreads in the brain. By combining imaging, gene data, and advanced modeling, researchers uncovered four gene pathways that either amplify or resist tau buildup, depending on brain connectivity.

Featured Neurology Neuroscience

·July 9, 2025·8 min read

How Fast Your Brain Ages Could Determine Your Future Health

A new study reveals that our organs age at different speeds, and those differences can predict future disease risk and even life expectancy. Using blood-based protein signatures from over 44,000 participants, researchers developed an algorithm to estimate the biological age of 11 organ systems.

Featured Neurology Neuroscience

·July 1, 2025·6 min read

Brain Stimulation Reverses Synaptic Damage in Alzheimer’s

New research shows that low-intensity repetitive transcranial magnetic stimulation (rTMS) can restore key synaptic structures in mouse models of Alzheimer’s disease. The study found that axonal boutons—sites where neurons form connections—had reduced turnover in Alzheimer’s mice, indicating impaired brain plasticity. After a single rTMS session, the turnover of one bouton type significantly increased, matching levels seen in healthy mice.

Featured Genetics Neurology Neuroscience

·June 30, 2025·6 min read

Mimicking Exercise in the Brain Could Slow Cognitive Decline

While physical activity is known to slow cognitive decline in Alzheimer’s disease, many patients are unable to exercise due to frailty or advanced symptoms. A new study identifies a specific gene, ATPPIF1, that is reactivated through exercise and supports neuroplasticity in the brain.

Featured Neurology Neuroscience

·June 30, 2025·6 min read

Alzheimer’s May Disrupt Nerve Insulation Without Reducing Myelin

New research reveals that Alzheimer's disease may impair nerve function not by reducing myelin, but by altering the proteins at the critical interface between axons and their myelin sheath. Scientists found structural abnormalities in the paranode region, where myelin attaches to axons, including clogged nutrient channels and protein buildup that could block signal transmission.

Featured Neuroscience

·June 29, 2025·8 min read

Brain Criticality May Hold Key to Learning, Memory, and Alzheimer’s

New research proposes a unified theory of brain function based on criticality—a state where the brain teeters between order and chaos, allowing it to learn, adapt, and process information optimally. When the brain strays from this delicate balance, cognitive performance weakens, and neurological disorders such as Alzheimer’s may begin to take hold.

This shows an older person walking in a street and a brain.

Featured Neurology Neuroscience

·June 26, 2025·3 min read

Neighborhood Disadvantage Linked to Alzheimer’s Biomarkers and Inflammation

Living in disadvantaged neighborhoods may increase the risk of Alzheimer’s disease by elevating biomarkers associated with inflammation and neurodegeneration. A long-term study of 334 older adults found higher levels of tau and YKL-40, biomarkers linked to Alzheimer’s and brain inflammation, in people from less advantaged areas.

Featured Genetics Neurology Neuroscience

·June 25, 2025·5 min read

Newborns and Alzheimer’s Patients Share a Brain Protein Spike

A new study has revealed that newborn babies and Alzheimer’s patients both have elevated levels of the same protein, p-tau217, in their blood. While this protein is a key marker of brain degeneration in Alzheimer’s, in newborns it appears to support healthy brain growth and development.

Featured Genetics Neurology Neuroscience

·June 24, 2025·5 min read

Rare Mutation Shields Brain from Alzheimer’s by Silencing Inflammation

A rare genetic mutation known as APOE3-R136S, or the “Christchurch mutation,” appears to protect against Alzheimer’s disease by suppressing inflammatory signaling in the brain’s immune cells. Researchers found that this mutation dampens the cGAS-STING pathway, a key innate immune mechanism that is abnormally activated in Alzheimer’s and other neurodegenerative disorders.

Featured Neurology Neuroscience

·June 18, 2025·3 min read

Alzheimer’s Risk Linked to Increased Social Activity, Not Isolation

Contrary to popular belief, a new study suggests that people with a higher genetic risk for Alzheimer’s may become more socially engaged—not less. Researchers analyzed data from over 500,000 individuals and found that higher-risk participants reported lower social isolation and more positive family interactions.