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Alzheimer’s disease

Featured Genetics Neurology Neuroscience

·September 28, 2023·10 min read

Breakthrough on Genetic & Molecular Drivers of Alzheimer’s

Researchers conduct the most extensive analysis on the genomic, epigenomic, and transcriptomic changes in Alzheimer’s patient brains. By analyzing over 2 million cells from 400 postmortem samples, they've uncovered a detailed picture of the disease's genetic and molecular foundation.

Featured Genetics Neurology Neuroscience

·September 18, 2023·5 min read

Mystery Behind Neuron Death in Alzheimer’s Decoded

Researchers have unveiled the mystery behind neuron death in Alzheimer's disease. A groundbreaking study reveals that neurons undergo a programmed cell death, necroptosis, when exposed to amyloid plaques and tau tangles, hallmark proteins linked to Alzheimer's.

Featured Neurology Neuroscience

·September 13, 2023·7 min read

Sit Less, Think More: Over 10hr Sedentary Time A Day Hike Dementia Risk

Adults over 60, who engage in more than 10 hours of sedentary behavior daily, have a heightened risk of dementia. The study revealed that the pattern of sedentary behavior throughout the day mattered less than the total hours spent.

Featured Neurology Neuroscience

·September 13, 2023·8 min read

Could a Brain Pathobiome Be The Hidden Culprit in Alzheimer’s Development?

New research points to the possibility that the development of a pathobiome in the brain could play a role in Alzheimer's and related dementias. Studying brain samples, researchers discovered Alzheimer’s-affected brains had markedly different bacterial profiles compared to non-affected peers.

Featured Neurology Neuroscience

·September 8, 2023·4 min read

Exercise Induced Hormone May Be Key Player in Alzheimer’s Fight

The muscle hormone irisin, elevated during exercise, may aid in battling Alzheimer's disease (AD). Using advanced 3D cell models of AD, the research demonstrates that irisin treatment drastically reduces amyloid beta pathology.

Featured Genetics Neurology Neuroscience

·September 6, 2023·5 min read

New Alzheimer’s Genetic Markers Unearthed

Researchers unearthed fresh gene variations related to Alzheimer’s disease risk, potentially paving the way for predictive blood tests. The study, targeting the APOE gene, identified 15 new variations linked to Alzheimer's likelihood.

Featured Neurology Neuroscience

·September 5, 2023·5 min read

Iron Buildup Triggers Cell Death in Alzheimer’s

Researchers identified a new form of cell death, termed ferroptosis, in Alzheimer’s disease and vascular dementia. This process involves the destruction of microglia cells—brain immune cells—due to the accumulation of iron.

Featured Neurology Neuroscience

·September 3, 2023·5 min read

Multiple Sclerosis Drug Shows Promise as New Alzheimer’s Therapy

A groundbreaking revealed that ponesimod, a drug originally used to treat multiple sclerosis, shows potential in treating Alzheimer’s disease. Researchers found that the medication reduces neuroinflammation, a critical factor in Alzheimer’s progression.

Featured Neurology Neuroscience

·August 31, 2023·6 min read

Two-Step Blood Test Sharpens Alzheimer’s Diagnosis

Researchers have developed a two-step workflow using a new blood-based p-tau217 biomarker to improve the accuracy of Alzheimer's Disease (AD) diagnosis. The first step uses a diagnostic model that combines plasma p-tau217 with age and the APOE e4 gene to identify high-risk patients.

Featured Neurology Neuroscience

·August 30, 2023·3 min read

Educational Buffer: How Learning Slows Genetic Alzheimer’s Risk

Researchers examined the role of genetics and educational attainment in early-onset Alzheimer's disease, specifically focusing on carriers of the PSEN1 E280A mutation. They found that carriers with an additional high-risk mutation, APOE e4, experienced faster cognitive decline, while those with a protective APOE e2 mutation had delayed onset.

Featured Genetics Neurology Neuroscience

·August 30, 2023·9 min read

Could A Gene Be A Hidden Shield Against Alzheimer’s & Parkinson’s?

Researchers identified a gene allele, known as DR4, that offers more than a 10% average reduction in the risk of Alzheimer's and Parkinson's diseases. The study, involving hundreds of thousands of people from various ancestries, suggests a potential role of the tau protein in both conditions.

This shows an older couple walking in a park.

Featured Neurology Neuroscience

·August 29, 2023·3 min read

Small Steps, Big Change: How Light Activity Could Guard Against Alzheimer’s

Researchers will explore how light physical activities like walking can affect cognition in older adults at risk for Alzheimer's or related dementias. Unlike previous studies that focused on the total amount of light activity, the research will examine day-to-day variations in light physical activity.

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Alzheimer’s disease

Breakthrough on Genetic & Molecular Drivers of Alzheimer’s

Mystery Behind Neuron Death in Alzheimer’s Decoded

Sit Less, Think More: Over 10hr Sedentary Time A Day Hike Dementia Risk

Could a Brain Pathobiome Be The Hidden Culprit in Alzheimer’s Development?

Exercise Induced Hormone May Be Key Player in Alzheimer’s Fight

New Alzheimer’s Genetic Markers Unearthed

Iron Buildup Triggers Cell Death in Alzheimer’s

Multiple Sclerosis Drug Shows Promise as New Alzheimer’s Therapy

Two-Step Blood Test Sharpens Alzheimer’s Diagnosis

Educational Buffer: How Learning Slows Genetic Alzheimer’s Risk

Could A Gene Be A Hidden Shield Against Alzheimer’s & Parkinson’s?

Small Steps, Big Change: How Light Activity Could Guard Against Alzheimer’s

Neuro-Insights of the Week From Neuroscience News, October 1, 2023

Circadian Rhythm Off Beat: Parkinson’s and Nighttime Neuron Damage

ChatGPT’s Role in Shaping Identity and Personal Narratives

New Brain Structures in Language Processing Identified

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