Solanezumab, an investigational anti-amyloid treatment, does not significantly slow the cognitive decline associated with Alzheimer's disease.
Researchers have developed a new method that uses antibody fragments encapsulated in nanomicelles which can cross the blood-brain barrier and reduce levels of amyloid-beta in the brains of mouse models of Alzheimer's disease.
People who follow diets rich in leafy greens, olive oil, nuts, and fish, such as the MIND or Mediterranean diet, have fewer amyloid plaques and Tau tangles in their brains than those who follow a more conventional diet.
Targeting and reducing the methylation of a key mRNA promoted the migration of macrophages in the brain and can improve cognitive symptoms of Alzheimer's disease.
As the brain ages, microglia adopt dysfunctional states that increase the risk of developing neurodegenerative diseases such as Alzheimer's disease.
Smoking may be a key risk factor for the development of dementia, but many smokers do not realize quitting cigarettes can help to reduce dementia risks.
Using neuroimaging data, a new deep-learning algorithm was able to detect Alzheimer's disease with 90.2% accuracy.
Researchers have developed a compound that can target and break down a post-transitionally modified protein associated with Alzheimer's disease.
Taking a vitamin D supplement daily may help stave off dementia in older adults, a new study reports. Researchers found taking vitamin D was associated with adults living dementia free for longer, and there were 40% fewer cases of dementia reported in those who frequently took vitamin D supplements. The effects were significantly greater in women than men.
Children who experience frequent nightmares at age 11 are twice as likely to develop symptoms of cognitive impairment, and seven times more likely to develop Parkinson's disease by age 50.
In those with Alzheimer's disease, the choroid plexus becomes enlarged and has increased accumulation of abnormal inflammatory signatures.
People with chronic pain in multiple parts of the body have a higher risk of developing dementia and accelerated cognitive decline.
