New abortion bans and restrictions could result in life-threatening consequences for women of childbearing age with epilepsy, multiple sclerosis, and migraine due to restrictions placed on their ability to access life-saving medications. Patients in states with strict abortion restrictions are reporting they are unable to access teratogenic drugs to treat their conditions, including methotrexate, as the medications can induce abortion.
Valproic acid (VPA), an anti-convulsant medication, can cause birth defects when taken during pregnancy. Researchers identified a molecule called p19Arf that appears to be responsible for VPA's induced senescence in neuroepithelial cells. When exposed to VPA, mice lacking p19Arf did not experience gene expression alterations associated with ASD.
Stimulating a part of the auditory cortex called the planum temporale improved speech perception, researchers report.
A newly designed compact device for recording brain activity has a customizable configuration and could help people with restricted mobility regain control of their limbs or provide advanced warnings of epileptic seizures.
Optogentic stimulation has the potential to cultivate resilience to epileptic seizures in animal models, researchers report.
Children with autism have abnormally low levels of the CNTNAP2 protein. The protein, which can be detected in cerebrospinal fluid samples, may serve as a new biomarker for autism and could potentially become a target to treat epilepsy that is commonly associated with ASD.
Deficits in the dentate gyrus function that causes memory problems may be associated with epileptic seizures a new study reports. The abnormal activity leads to over-extinction, spurring on seizures.