Study reveals the surface features of human prions responsible for their replication in the brain. The findings provide a template to identify structurally important sites on other misfolded proteins, such as those associated with Alzheimer's disease.
Researchers found an increased inflammatory signal in patients with the C90rf72 subtype of ALS. The increased inflammatory biomarkers could be found in peripheral serum tests.
P-glycoprotein, a critical toxin pump in the body, has the ability to remove amyloid plaques from the brain. Researchers say increasing P-gp in the blood-brain barrier of those at risk for Alzheimer's could postpone or prevent the onset of the neurodegenerative disease.
Study reveals the significant role lipids play in regulating the amyloid pathway protein C99 and the progression of Alzheimer's disease.
Elderly monkeys treated with CpG ODN had 59% fewer deposits of Alzheimer's related plaques in their brains compared to those who did not receive the treatment. The treatment also helped improve cognitive function and slow the progression of Alzheimer's symptoms.
A review of Alzheimer's research papers finds news media is more likely to report on breakthroughs if the study's authors omit a reference to mice in their title. Papers that acknowledge mice in their title receive less media coverage. Omitting mice from a paper's title generates twice the number of tweets than ones that mention the animals.
COVID-19 can spark a severe immune response in the central nervous system, affecting immune cells in the vascular system and brain.
Researchers have identified a causal link between strenuous exercise and ALS in people with genetic risk factors for the neurodegenerative disease. The study reports intense physical exercise contributes to motor neuron injury in those susceptible to ALS.
Commonly associated with helping improve brain function, the omega 3 fatty acid DHA may have another, previously unknown benefit. A new study reports DHA and other related fatty acids may help slow the development of cancerous tumors.