A majority of Parkinson's patients report a diminished sense of smell, which starts to occur a number of years before the onset of other symptoms. Researchers are exploring whether scent-processing neurons which connect the nose to the brain may play a role in the development of Parkinson's disease.
Bach1, a protein that blocks the expression of genes associated with neuroprotection, has been implicated in Parkison's disease. Researchers say blocking Bach1 slows the deterioration of brain cells in preclinical models of Parkinson's disease.
While the positive impact of breastfeeding on babies is well known, little is known about the positive benefits for the mother. A new study reveals women who breastfed their children performed better on cognitive tests at age 50 than those who fed their children with an alternative method.
While a low-protein diet can accelerate neurodegeneration, consuming Amino LP7, a combination of essential amino acids, could slow the progression or inhibit the development of dementia.
Mirtazapine, an antidepressant commonly prescribed to treat dementia-associated agitation, is no more effective than a placebo and may increase mortality risks, researchers report.
A new study reveals how adipocytes, or fat cells, play a role in cognitive decline and increased neurodegeneration risks. Using genetically modified mouse models, researchers found oxidative stress through exposure to a Western diet increased the production of inflammatory cytokines confined to adipocytes and altered protein markers of memory and cognition in the hippocampus.
Fenofibrate, an FDA-approved drug commonly used to treat high cholesterol, activated support cells around sensory neurons in mouse models of spinal cord injury, helping them regrow twice as fast as a placebo.
Some viral infections could increase intercellular spreading of protein aggregates associated with neurodegenerative disorders, increasing the risk for developing Alzheimer's, Parkinson's, and other neurodegenerative diseases.