Fenofibrate, an FDA-approved drug commonly used to treat high cholesterol, activated support cells around sensory neurons in mouse models of spinal cord injury, helping them regrow twice as fast as a placebo.
Some viral infections could increase intercellular spreading of protein aggregates associated with neurodegenerative disorders, increasing the risk for developing Alzheimer's, Parkinson's, and other neurodegenerative diseases.
A new rodent study uncovers a neural circuit in the brain that appears to govern pain-induced anhedonia. Altering the activity of this circuit restored motivation in pre-clinical models of pain.
Variations in the TSPO neuroinflammation-associated protein's structure correlates with worse survival outcomes for male glioblastoma brain cancer patients than females.
Study reveals a causal mechanism for pain reduction may be due to an antibiotic-induced shift in the gut's amino acid concentrations.
Study reveals microglia play an important role in the maintenance of blood delivery to the brain. The findings may prove important to the study and treatment of cognitive decline, dementia, and stroke.
A diet high in processed foods leads to neuroinflammation and memory decline in older rats, a new study reports. Supplementing a processed food diet with DHA, an omega 3 fatty acid, helped mitigate memory problems and reduce inflammation.
In the early stages of neurodegenerative diseases, microglia consume glucose to a greater extent than previously believed. The findings may serve as a new biomarker for a range of neurodegenerative disorders.
A new study adds additional evidence to the link between personality traits and Alzheimer's risk. Researchers found brain changes associated with Alzheimer's are visible early on in people with certain personality traits. Those who scored high for neuroticism and low in conscientiousness were at increased risk of developing Alzheimer's.
Researchers have identified causal genetic links to three blood metabolite levels that increase migraine risks.