A subtle increase of the PKCα protein produces biochemical, cellular, and cognitive impairments akin to those seen in Alzheimer's disease. The finding provides a potential new target for the treatment of the neurodegenerative disorder.
Previous TBI increased the risk of frontotemporal dementia in those without a genetic risk factor for FTD. Additionally, researchers found those with FTD tend to be less educated than those with Alzheimer's disease.
Persistent asthma in adults was associated with increased inflammation and an excess build-up of plaques in the carotid arteries, increasing the risk of heart attack and stroke.
Researchers have identified two new genes, ATP8B4 and ABCA1, that are implicated in Alzheimer's disease. The genes impact the brain's immune system and cholesterol processing, leading to an increased risk of developing Alzheimer's disease.
Increasing consumption of food and drinks high in antioxidant flavonols helps slow memory and cognitive decline, a new study reports.
Researchers have developed a family of adeno-associated viral vectors (AAVs) that are able to cross the blood-brain barrier to deliver gene therapies directly to the brain.
Results of a phase three clinical trial of a novel brain cancer vaccine, DCVax-L, that uses a patient's stem cells to target cancer cells extend survival by many months to years for glioblastoma patients.
Neuroimaging study reveals significant brain changes in areas associated with language comprehension, cognition, and circadian rhythm control six months after COVID-19 infection.