On average, women who self-harm have a higher tolerance to pain than those who do not self-injure. Brain scans revealed greater connectivity between brain areas involved in pain perception and pain modulation in those who self-harm.
Researchers identified LIPE, a lipase that degrades triglycerides to produce fatty acids, as a potential new target for the development of treatments for Parkinson's disease.
People who suffer cardiometabolic disorders, such as stroke, diabetes, or a heart attack, either as stand-alone conditions or a combination of the conditions, have an increased risk of developing dementia regardless of whether or not they have a genetic predisposition for neurodegeneration.
Despite speculation that inflammation associated with the shingles virus can increase dementia risk, researchers found little evidence to substantiate the claim.
People with higher levels of omega-3 DHA in their blood are 49% less likely to develop dementia than those with lower levels. Researchers say adding additional omega-3 DHA to the diet, especially in those with the Alzheimer's associated Apoe4 gene, could slow the development and progress of dementia.
The Parkinson's-associated protein alpha-synuclein appears to act as a "toggle switch" that helps control vesicle transportation and gene expression. In a diseased state, this delicate balance is broken. The findings have implications for the development of new treatments for Parkinson's disease.
Takotsubo syndrome, a sudden form of acute heart failure often brought on by emotional or physical stress, is associated with changes in brain regions associated with emotion and emotional processing.
Social isolation has been directly linked to structural changes in brain areas associated with memory and cognitive function. Researchers report socially isolated people are 26% more likely to develop dementia later in life.
Older adults who frequently experience bad dreams or nightmares are twice as likely to be diagnosed with Parkinson's disease, a new study reports.
Neurons in the parafascicular thalamus project to three different parts of the basal ganglia. Targeting these circuits could be a new target for treating motor dysfunction and depression associated with Parkinson's disease.