In rheumatoid arthritis, inflammation in one joint is transmitted to other joints via the sensory neuron connections in the spinal cord, leading to inflammation in the other joints. Inflammation in one joint led to an increase in ATP in other joints, which triggered an increase of a signaling molecule that resulted in inflammation. Blocking the pathway reduced the spread of inflammation.
Researchers have identified a mechanism that occurs within the CA3 region of the hippocampus that appears to be responsible for a common type of age-related memory loss.
Most cancer patients who used medical cannabis reported a significant improvement in pain measures and a decrease in some other cancer-related symptoms. Additionally, medical cannabis use reduced the consumption of traditional, opioid-based pain killers for those with cancer.
Volume decreases in cortical areas, the amygdala, and basal forebrain in Parkinson's patients correlated with worsening symptoms of the disease.
A new study reports that increased volume in the choroid plexus appears to be associated with greater cognitive impairment and Alzheimer's disease.
A new computer model shows the beneficial effects of deep brain stimulation arise from how it interrupts the cycle promoting runway beta in a circuit loop between the subthalamic nucleus and striatum.
Sleep continuity, in addition to sleep quality, can determine how a person with dementia will experience their symptoms the next day.
A combination of patient-reported subjective cognitive impairment and measurable clinical symptoms, such as amyloid-beta accumulation in the cerebrospinal fluid, may help in the early diagnosis of Alzheimer's disease.