Almost 50% of women who experience hyperemesis gravidarum, or extreme morning sickness, develop depression while pregnant. 30% report symptoms of postnatal depression. Read More
STAT3 plays a crucial role in the serotonergic system as a molecular mediator for controlling emotional reactivity. The findings establish a link between the immune system, serotonergic transmission, and affective disorders such as depression. Read More
p11, a protein implicated in serotonin function, affects the initial release of cortisol in mice by modulating the activity of specific neurons in the hypothalamus. Previous studies found people with depression lave lower levels of p11 in their brains. The findings could help in the development of new treatments for depression and stress. Read More
Study reveals a link between people with depression who are prescribed newer antipsychotic medications and higher mortality risk. Read More
Older adults who took brief, weekly "awe walks" for eight weeks reported improvements in positive emotions and a decrease in daily life stress. Read More
Researchers link the rise in acute stress and depression rates in the U.S to multiple stressors, such as unemployment and coronavirus-related media consumption. Read More
Gamma interferons, a type of immune cell that induces and modulates several immune system responses, may also play a role in preventing depression. Read More
While numerous researchers have concluded that diet can help prevent or alleviate symptoms of depression, a new study reports the evidence to support such claims is weak. Read More
Researchers have uncovered the structure of psychedelic compounds when they actively bind to the 5-HT2A serotonin receptor on the surface of brain cells. The discovery could lead to the exploration of more precise compounds that offer the therapeutic effects of psychedelics for mental health disorders, but without the hallucinations. Read More
People with depression and a history of physical disease are at increased risk of their disease symptoms worsening and requiring hospitalization. Read More
Depression and anxiety have different biochemical links to inflammation and lipid metabolism. Those with depression have greater levels of inflammation and different types and amounts of lipids in their blood compared to those with anxiety. The metabolites associated with depression were linked to the severity of symptoms. Higher levels of lipids associated with depression detected in a person's blood correlated with more severe symptoms. Read More
Data collected from smartphones can accurately predict connectivity between brain regions associated with emotional processing. Analyzing cellphone data, such as social activity, screen time, and location, alongside fMRI brain scans, researchers found smartphone data activity mirrors brain activity associated with depression and anxiety. Read More
