Mouse study reveals chronic stress affects neurogenesis in the dentate gyrus.
In the absence of neural activity, BDNF expression can still be activated. The findings shed light on how therapeutic ketamine used has an antidepressant effect and how it works in both the long and short term.
People who receive threatening or obscene text messages and other communications from current or former partners are more likely to experience mental health problems including depression and anxiety, and have an increased risk of suicidal thoughts.
There is a growing body of evidence linking depression to microbiome health. A new study proposes focusing on the microbiome may help alleviate some of the symptoms of depression associated with the COVID-19 pandemic.
Allopregnanolone, a neuroactive steroid used in the treatment of postpartum depression, alters neural communication in the basolateral amygdala, an area of the brain associated with emotion and mood regulation. The drug may alter the network associated with chronic stress, which may explain its persistent antidepressant effect.
Hearing loss was associated with an increased risk of depression in older adults. Those of lower socioeconomic status were twice as likely to report symptoms of depression. However, using hearing aids helped alleviate symptoms of depression.
A new study adds to the growing body of research linking inflammation to depression. Researchers found the molecule histamine directly inhibits the release of serotonin in the brain by attaching to inhibitory receptors on serotonin neurons in mice.
Both physical and social factors play significant roles in depression and reports of poor wellbeing associated with obesity.
Researchers report essential oils may help improve mood and symptoms in those with anxiety and depression due to anti-oxidant effects on the brain.
People with no prior mental health diagnosis who contract Lyme disease have a 42% higher risk of developing an affective disorder, such as depression, and a 75% higher rate of death by suicide than those without the disease.
Phubbing, a behavior where people snub their friends in favor of looking at their cell phones, may be linked to depression and anxiety. The behavior is most common in those with higher levels of neuroticism.