bipolar disorder

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bipolar disorder

·July 7, 2020

Brain Structural Elements in Psychiatric Disorders

Comparing data from multiple neuroimaging studies, researchers found shared brain structural abnormalities between four psychiatric disorders, including schizophrenia and bipolar disorder. They also identified brain signatures unique to each condition. Read More

Featured Genetics Neuroscience

·March 26, 2020

Genetic architecture of gray matter revealed

A worldwide scientific collaboration has produced the first genetic map of the cerebral cortex. The map identifies more than 300 genetic variants that influence cortical structure and play roles in psychiatric disorders. Read More

Featured Genetics Neuroscience Open Neuroscience Articles Psychology

·March 9, 2020

The largest genetic map of psychiatric disorders so far

The largest genetic map of mental health disorders to date reveals there are three groups of highly genetically related disorders among eight psychiatric disorders. A gene related to nervous system development is a risk factor for all eight disorders studied. The RBFOX1 gene is implicated in seven of the eight disorders. ADHD and depression share 44% of genetic risk factors common in the general population. 109 pleiotropic loci affect more than one disorder. These pleiotropic loci are within genes that show heightened expression in the brain through the lifespan, beginning during the second trimester of pregnancy. Read More

Featured Neurology Neuroscience pain Psychology

·February 28, 2020

Overdosing on psychedelics improved mental and physical health: Case studies

A recent case study report highlights the effects of LSD overdoses on three women, revealing the subjects experienced improvements in physical and mental health following their overdoses. Read More

This is a diagram of the subtypes of psychosis

Featured Neuroscience Psychology

·February 24, 2020

Five different subgroups of bipolar and psychosis identified

Computer analysis of patients reveals five clearly defined subgroups of psychosis and bipolar disorder. Those in group two were more likely to exhibit suicidal tendencies, while those in group five, for example, were characterized by schizophrenia diagnosis and lower verbal intelligence scores. Defining the characteristics of the subtypes could lead to improved personalized treatments for psychosis related mental illnesses. Read More

Electrophysiology Featured Neuroscience Psychology

·February 19, 2020

Altered potassium levels in neurons may cause mood swings in bipolar disorder

Increased potassium currents were responsible for hyperactivity of CA3 neurons. When exposed to potassium channel blockers, the hyperactivity disappeared. However, when exposed to lithium, the drug not only reversed hyperactivity but reduced potassium currents at the same time. The findings strengthen the case that potassium currents play a role in bipolar disorder. Read More

Featured Genetics Neuroscience Psychology

·February 12, 2020

Multi-center neuroimaging study offers new insights on schizophrenia

Those with 22q11.2 deletion syndrome had significantly lower brain volume, as well as lower volumes in specific structures, including the thalamus, hippocampus, and amygdala. Read More

Featured Genetics Neuroscience Open Neuroscience Articles Psychology

·February 12, 2020

Circular reasoning: Reduced levels of circHomer1a associated with mental health disorders

Lower levels of the circular RNA in the frontal cortex appears to be correlated with earlier onset of schizophrenia symptoms. Read More

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Featured Neuroscience Psychology

·February 4, 2020

Light therapy holds promise for people with bipolar disorder

Daily exposure to bright, artificial light may help reduce symptoms of bipolar disorder. Read More

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Featured Genetics Neuroscience Open Neuroscience Articles Psychology

·January 29, 2020

Genetics contributes to mental health risks in adoptees

Study reports a slightly elevated genetic risk of depression, schizophrenia, and neuroticism among adoptees. However, no association was found between the interaction of genetics and adoption on mental health. While adopted children had a slightly elevated risk for mental health disorders, the adoption process did not appear to increase the impact of the genetic risk. Read More

Featured Genetics Neuroscience Psychology

·January 22, 2020

Study explores cognitive function in people with mental illness

Study finds few differences in the profiles of genes that influence cognition between those with severe mental health disorders and the general population. Read More

This shows a man sitting alone in a street at night time

Featured Neuroscience Psychology

·January 16, 2020

Lifetime suicide risk factors identified

Analyzing previous studies, researchers have identified the effects of individual and environmental risk factors for suicide over a person's lifespan. The risk factors, researchers report, change throughout a person's lifetime. Read More

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