People with bipolar disorder who also suffer PTSD following trauma, or who have a genetic predisposition to PTSD may be at greater risk for death by suicide.
Findings reveal a role the endocannabinoid system plays in a range of psychiatric disorders, including schizophrenia, bipolar disorder, and ASD.
A link has been identified between psychosis and a genetic change that alters the immune system in the brain. Researchers found people with psychosis associated with bipolar disorder had decreased expression of GRK3. This led to an increased amount of kynurenic acid in the brain.
Almost fifty percent of people who have children with partners suffering from schizophrenia or bipolar disorder also have mental health challenges, a new study reports.
A new blood test can distinguish the severity of a person's depression and their risk for developing severe depression at a later point. The test can also determine if a person is at risk for developing bipolar disorder. Researchers say the blood test can also assist in tailoring individual options for therapeutic interventions.
Disruptions in the Atk protein can lead to brain changes that are characteristic of bipolar disorder.
Research has long revealed an association between belief in conspiracy theories and mental health disorders. A new study reports followers of the radical QAnon group are significantly more likely to suffer from mental health problems, including depression, anxiety, and schizophrenia, than the general population.
Researchers found that while there are genetic overlaps between the sexes in relation to mental health disorders, there are also sex-specific differences in how genes related to the immune system, central nervous system, and blood vessels affect people with mental health problems.
Anti-psychotic drugs do not only block dopamine signaling in the brain, they also block dopamine signaling in the pancreas. Blocking dopamine signaling in the pancreas leads to uncontrolled production of blood-glucose regulating hormones, increasing obesity and diabetes risks.
Differences in the expression of gene transcripts shed light on how mental health disorders with shared genetic risk factors differ in onset, symptoms, course of progression, and treatment responses.
Decreased activation of the LEF1 gene is more common in bipolar patients who do not respond to lithium.
White matter connectivity does not directly induce psychosis, but may affect symptoms of psychosis through its effect on the consciousness threshold.
