Cortical thinning over time was associated with bipolar patients who experienced more manic episodes. The changes were most evident in the prefrontal cortex, an area of the brain associated with emotional control and executive function.
People living with common allergies such as asthma, hay fever, and atopic dermatitis are at greater risk of developing depression, bipolar disorder, anxiety, and neuroticism. Researchers report the link was likely not causal.
People with bipolar disorder who experience frequent manic episodes had faster cortical thinning, specifically in the prefrontal cortex than those who reported less frequent episodes of mania. Researchers also noted faster enlargement of the brain's ventricles and slower thinking of the parahippocampal and fusiform cortical regions in those who experienced more frequent mania.
An experimental diet that reduced the intake of omega-6 fatty acids and increased omega-3 fatty acids improved mood variability in those with bipolar disorder.
Dialectical behavior therapy (DBT) appears to be a feasible and acceptable therapy to help with mood regulation in those with bipolar disorder.
People with bipolar disorder who also suffer PTSD following trauma, or who have a genetic predisposition to PTSD may be at greater risk for death by suicide.
A link has been identified between psychosis and a genetic change that alters the immune system in the brain. Researchers found people with psychosis associated with bipolar disorder had decreased expression of GRK3. This led to an increased amount of kynurenic acid in the brain.
Almost fifty percent of people who have children with partners suffering from schizophrenia or bipolar disorder also have mental health challenges, a new study reports.
A new blood test can distinguish the severity of a person's depression and their risk for developing severe depression at a later point. The test can also determine if a person is at risk for developing bipolar disorder. Researchers say the blood test can also assist in tailoring individual options for therapeutic interventions.
Disruptions in the Atk protein can lead to brain changes that are characteristic of bipolar disorder.