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bipolar disorder

Featured Genetics Neuroscience Open Neuroscience Articles Psychology

·March 9, 2020·7 min read

The largest genetic map of psychiatric disorders so far

The largest genetic map of mental health disorders to date reveals there are three groups of highly genetically related disorders among eight psychiatric disorders. A gene related to nervous system development is a risk factor for all eight disorders studied. The RBFOX1 gene is implicated in seven of the eight disorders. ADHD and depression share 44% of genetic risk factors common in the general population. 109 pleiotropic loci affect more than one disorder. These pleiotropic loci are within genes that show heightened expression in the brain through the lifespan, beginning during the second trimester of pregnancy.

Featured Neuroscience Psychology

·July 7, 2020·4 min read

Brain Structural Elements in Psychiatric Disorders

Comparing data from multiple neuroimaging studies, researchers found shared brain structural abnormalities between four psychiatric disorders, including schizophrenia and bipolar disorder. They also identified brain signatures unique to each condition.

Featured Genetics Psychology

·March 29, 2014·2 min read

Genetic Model for Bipolar Treatment

According to new findings, lithium's therapeutic effects stems from its suppression of myo-inositol.

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Featured Neuroscience Open Neuroscience Articles Psychology

·June 11, 2019·3 min read

Brain activation provides individual-level prediction of bipolar disorder risk

Combining neuroimaging data with machine learning, researchers have identified patterns of brain activation during reward anticipation, associated with an increased risk of developing bipolar disorder. The patterns of neural activation predict the severity of mania symptoms in young adults who have not yet developed the disorder.

Featured Genetics Psychology

·August 25, 2020·5 min read

One Step Closer to Earlier Diagnosis of Bipolar Disorder and Psychoses

Genetic risk score for bipolar disorder is associated with an increased risk of developing bipolar symptoms. The genetic risk factor for schizophrenia is linked to an increased risk of those with depression developing psychosis.

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Featured Neuroscience Psychology

·February 4, 2020·4 min read

Light therapy holds promise for people with bipolar disorder

Daily exposure to bright, artificial light may help reduce symptoms of bipolar disorder.

Featured Genetics Psychology

·June 20, 2018·4 min read

Shared Genetics May Shape Treatment Options for Certain Brain Disorders

Researchers report common symptoms of bipolar depression and schizophrenia, such as depression, psychosis and mania, have shared and distinguished genetic risk factors. The findings could help with the development of more effective therapies for these neuropsychological disorders.

Featured Neuroscience Psychology

·April 1, 2021·6 min read

Disrupted Biochemical Pathway in the Brain Linked to Bipolar Disorder

Disruptions in the Atk protein can lead to brain changes that are characteristic of bipolar disorder.

Featured Genetics Psychology

·February 5, 2016·3 min read

A Molecular Link Between Type 2 Diabetes and Some Psychiatric Disorders

A new study reports DISC1, a gene that plays a role in some psychiatric illnesses, also influences the production of insulin creating pancreatic beta cells.

Featured Neuroscience Open Neuroscience Articles Psychology

·May 12, 2021·4 min read

Brain Immune System Linked to Psychosis

A link has been identified between psychosis and a genetic change that alters the immune system in the brain. Researchers found people with psychosis associated with bipolar disorder had decreased expression of GRK3. This led to an increased amount of kynurenic acid in the brain.

Featured Psychology

·October 7, 2018·3 min read

Diet and Weight May Affect Bipolar Treatment Response

Researchers report diet and weight may hinder the response to medications for some with bipolar disorder. The study found those who had a better quality of diet and lower BMI responded better to treatments than those who were overweight and ate foods that promoted inflammation.

Featured Neuroscience Open Neuroscience Articles Psychology

·April 14, 2022·6 min read

Your Mental Health May Impact Your Chances of Breakthrough COVID

Vaccinated people with a history of mental health disorders including bipolar disorder, psychosis, and anxiety, have a 24% increased risk of contracting COVID-19, a new study reports.

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