Lower cholesterol levels may put people with schizophrenia at higher risk for violent behaviors, including self-harm and suicide. Researchers say lower cholesterol levels make brain cells less sensitive to serotonin, increasing symptoms of depression, impulsivity, and aggression.
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Blood tests revealed specific epigenetic biomarkers for schizophrenia. Researchers applied machine learning to analyze the CoRSIVs region of the human genome to identify the schizophrenia biomarkers. Testing the model with an independent data set revealed the AI technology can detect schizophrenia with 80% accuracy.
Findings reveal how individual neurons in the thalamus can merge signals coming from different regions of the cortex. The findings could lead to new treatment options for schizophrenia, epilepsy, and other brain disorders where thalamus dysfunction is related to clinical symptoms.
Study reveals how the amygdala plays a role in prepulse inhibition by activating inhibitory neurons in the brain stem of mice. The findings could have positive implications in the development of treatments for schizophrenia, OCD, and other disorders marked with impaired somatosensory gating.
Subtle differences in perception during teenage years predict the development of hallucinations, delusions, and psychosis later in life.
A new theory proposes an imbalance of blood proteins involved in the immune system and in blood clotting networks leads to inflammation that contributes to the development of psychosis.