Schizophrenia

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Schizophrenia

·June 6, 2021·4 min read

Functional Brain Network Predicts Real-Life Social Network in Both Individuals With Schizophrenia and Social Anhedonia

Patients with schizophrenia, but not those with social anhedonia, exhibited deficits in real-life social network size. Those with schizophrenia and those with social anhedonia had reversals functional connectivity to one another. People with schizophrenia showed decreased segregation and functional connectivity in brain areas associated with social behaviors, while those with social anhedonia had an increase in connectivity and segregation.

Featured Genetics Neuroscience Open Neuroscience Articles Psychology

·June 1, 2021·6 min read

Protecting the Intellectual Abilities of People at Risk for Psychosis

Prescribing SSRIs during late childhood to those with genetic risk factors for psychosis can reduce the deterioration of intellectual abilities, a new study reveals. SSRIs appear to have a neuroprotective effect for certain brain areas associated with the onset of psychosis if provided early.

Featured Neuroscience Open Neuroscience Articles Psychology

·May 31, 2021·4 min read

Low Levels of Omega-3 Associated With Higher Risk of Psychosis

Adolescents with higher levels of Omega 3 fatty acids in their blood had a decreased risk of developing psychosis as they entered into early adulthood. At the age of 24, those with psychosis had lower levels of DHA than those without the disorder.

Featured Neuroscience Open Neuroscience Articles Psychology

·May 25, 2021·4 min read

Vitamin B6 Deficiency Enhances the Noradrenergic System, Leading to Behavioral Deficits

Study reveals vitamin B6 deficiency may contribute to the development of schizophrenia symptoms.

Featured Neuroscience Psychology

·May 19, 2021·6 min read

Commonly Used Drugs for Schizophrenia Linked to Greater Cognitive Impairment

Medications with anticholinergic properties given to help reduce physical and mental health symptoms associated with schizophrenia have a cumulative effect in reducing cognitive function in patients.

Featured Genetics Neuroscience Psychology

·May 19, 2021·5 min read

Flies With Schizophrenia-Associated Genes Respond Well to Anti-Psychotics

Flies without the Rim gene or cac Cav2 channel function displayed numerous cognitive and behavioral deficits associated with schizophrenia, and had reductions in synaptic growth and neural calcium transients. Exposing the flies with Rim deficits to the common antipsychotic haloperidol reduced some of the schizophrenia-related behavioral symptoms.

Featured Neuroscience Open Neuroscience Articles Psychology

·May 12, 2021·4 min read

Brain Immune System Linked to Psychosis

A link has been identified between psychosis and a genetic change that alters the immune system in the brain. Researchers found people with psychosis associated with bipolar disorder had decreased expression of GRK3. This led to an increased amount of kynurenic acid in the brain.

Featured Neuroscience Psychology

·May 5, 2021·5 min read

Partners of People With Schizophrenia and Bipolar Disorder Have Often a Mental Disorder

Almost fifty percent of people who have children with partners suffering from schizophrenia or bipolar disorder also have mental health challenges, a new study reports.

Featured Neuroscience Open Neuroscience Articles Psychology

·May 5, 2021·4 min read

Study Links Brain Thinning to Psychosis

Adolescents with a higher risk for developing psychosis have subtle differences in brain structure, including lower cortical thickness than their peers without risk factors. In those who developed psychosis, the cortical thinning was most pronounced in several areas of the temporal and frontal regions of the brain.

Featured Neuroscience Psychology

·April 30, 2021·4 min read

Transporter Imbalance Implicated in Schizophrenia

Researchers have implicated alterations in the balance of two chloride ion channels in the cognitive deficits associated with schizophrenia. Inhibiting transporter activity with bumetanide reversed some of the cognitive symptoms in mouse models of the psychiatric disorder.

Electrophysiology Featured Neuroscience Psychology

·April 24, 2021·6 min read

The Immune Link Between a Leaky Blood-Brain Barrier and Schizophrenia

People with schizophrenia and other neuropsychiatric disorders may have a more permissive blood-brain barrier which allows the immune system to become more actively involved in the central nervous system. The resulting inflammation may contribute to the clinical manifestation of psychosis-like symptoms.

Featured Neuroscience Open Neuroscience Articles Psychology

·April 19, 2021·5 min read

Betaine Supplement Treats Schizophrenia in Mice

Betaine, a dietary supplement extracted from sweet beets, reduces behavioral symptoms of schizophrenia in mice with genetic risk factors for the disorder. The supplement may help protect proteins that build the cellular skeletons of neurons.

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