Schizophrenia itself is associated with loss of excitation, but hallucinations and other symptoms of the disorder are caused by a loss of synaptic inhibition.
White matter functional connectivity distributions may contribute to working memory and processing speed impairments in schizophrenia.
Researchers find a region of the brain stem called the periaqueductal gray may mediate religiosity and spirituality in humans.
Lower cholesterol levels may put people with schizophrenia at higher risk for violent behaviors, including self-harm and suicide. Researchers say lower cholesterol levels make brain cells less sensitive to serotonin, increasing symptoms of depression, impulsivity, and aggression.
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··5 min readBlood tests revealed specific epigenetic biomarkers for schizophrenia. Researchers applied machine learning to analyze the CoRSIVs region of the human genome to identify the schizophrenia biomarkers. Testing the model with an independent data set revealed the AI technology can detect schizophrenia with 80% accuracy.
Findings reveal how individual neurons in the thalamus can merge signals coming from different regions of the cortex. The findings could lead to new treatment options for schizophrenia, epilepsy, and other brain disorders where thalamus dysfunction is related to clinical symptoms.
Study reveals how the amygdala plays a role in prepulse inhibition by activating inhibitory neurons in the brain stem of mice. The findings could have positive implications in the development of treatments for schizophrenia, OCD, and other disorders marked with impaired somatosensory gating.
Subtle differences in perception during teenage years predict the development of hallucinations, delusions, and psychosis later in life.
Study reveals an abundance of the CRMP2 protein in people with schizophrenia. The findings could lead to a blood-based biomarker test for the mental health disorder.
A new model of schizophrenia opens the door to a better understanding of, and therapeutic options for brain dysfunction that is at the root of psychosis.
A new theory proposes an imbalance of blood proteins involved in the immune system and in blood clotting networks leads to inflammation that contributes to the development of psychosis.
The release of neurotransmitters in the brain is impaired in people with schizophrenia who have the neurexin 1 gene mutation.
