Study reveals the benefits of family involvement in treatment outcomes for those who suffer from psychosis.
Pro-inflammatory cytokines IL-1 beta and IL-6 stimulate the expression of the schizophrenia-related C4A gene. Patients with high C4A expression displayed increased levels of IL-1 beta in cerebral spinal fluid samples. C4A levels were also correlated with markers of synaptic density. Findings reveal inflammation enhances the genetic risk variant for schizophrenia.
People with schizophrenia and social anhedonia exhibit altered neural processing for social reward processing, leading to impaired social interaction and social dysfunction.
Study reveals a "hotspot" for schizophrenia in the upper prefrontal cortex of the brain. In this area, researchers identified distinct neural networks that may be responsible for the overall symptoms of schizophrenia.
People with schizophrenia are 2.5 times more likely to develop dementia than those without a mental health disorder.
During brain development, oligodendrocyte precursor cells (OPCs) contribute to the neural pruning process, helping to shape the healthy development of the brain.
Researchers report bipolar depression and schizophrenia may be detectable several years before symptoms appear. A new study reports 50% of patients diagnosed with schizophrenia or bipolar disorder attended specialist child and adolescent mental health services during childhood.
Study reveals a moderate link between antipsychotic use and an increased risk of developing breast cancer.
Using a Brief Negative Symptom Scale (BNSS) to assess negative symptoms of schizophrenia may bridge the gap between clinical interviews and a patient's self-reported measure of symptoms.
Young people with 22q11.2 Deletion Syndrome have distinct and marked EEG differences in brain activity during sleep, which could influence psychiatric symptoms.
Creating modular neural networks (MoMNets), researchers generate a new way to study schizophrenia and other disorders in a lab setting.
Study reveals striking similarities in both behaviors and neuroanatomical changes between people with schizophrenia and behavioral-variant frontotemporal dementia.