neurobiology

This shows VGLL3 expression in different skin samples

Skin discovery may help explain why women get autoimmune diseases far more often than men

Skin cells may hold the key to explaining why women are more prone to developing autoimmune diseases, such as lupus than men. Researchers found women have more VGLL3 in their skin cells than men. VGLL3 pushes the immune system into overdrive, resulting in the 'self-attacking' autoimmune response, the mouse study revealed. Findings strongly implicate VGLL3 as a pivotal catalyst in sex-based autoimmunity.... Read More...
This is a drawing of a gilt head bream

Fish are accumulating certain antidepressants, antibiotics and sun cream components

Antidepressants, such as the SSRI amitriptyline, antibiotics associated with developmental problems and sun cream components are contaminating water, and are being accumulated in fish. Exposure to the medications has effects on the molecular level to the fish. Researchers say this poses a problem as consumption of gilt-head bream is on the rise, and there could be a risk of the contaminants reaching humans via diet.... Read More...
This shows a pill bottle

Blood pressure drug shows promise for treating Parkinson’s and dementia in animal study

Felodipine, a common hypertension medication, induces autophagy and clears aggregate-prone proteins associated with neurodegenerative diseases. The study reveals the drug clears mutant alpha-synuclein in the brains of mice at plasma concentrations to those seen in humans taking the medication. Felodipine appears to have some neuroprotective properties in mouse models of neurodegenerative diseases.... Read More...