Children suffering from a form of autism called ADNP syndrome may benefit from an experimental drug designed to treat Alzheimer's disease. Read More
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Mapping the thalamic reticular nucleus, researchers have identified two distinct subnetworks of neurons with different functions. Findings offer insight into more specific targets for therapeutics to alleviate some sensory, sleep, and attention symptoms associated with ASD and other disorders characterized by sensory hypersensitivity. Read More
Study reveals how two neural circuits dictate the choice between social approach and avoidance. The network connecting the infralimbic cortex to the basolateral amygdala (BLA) impairs social behavior if there is a decrease in neural activity. Another network connecting the prelimbic cortex to the BLA similarly impairs social behavior if the neural activity is increased. Read More
Early developmental deficits in the formation of the brain's blood vessels cause autistic traits in mouse models of ASD. Read More
The loss of the protein neurofibromin 1 (NF1) in adult male flies resulted in social impairments. The deficits were traced back to a primary disruption in a small group of peripheral neurons which control external stimuli, including touch and smell, that communicate to the brain. Read More
Mutations of the CNOT1 gene affect brain development, impairing memory, and learning. The CNOT1 gene also interacts with several known autism-related genes. Read More
Blood samples reveal unique metabolic signatures in over 50% of children on the autism spectrum. Read More
Abnormal sensory processing associated with ASD has been linked to weaker neural suppression in the visual cortex. Read More
A new study reveals up to 30% of children diagnosed with autism had less severe symptoms at age six than they did at age three. In some cases, children lost their autism diagnoses entirely. Girls are more likely to show a greater reduction in autism symptoms and less of a rise in the severity of symptoms than boys on the autism spectrum. Read More
Rat study suggests prenatal microbial exposure influences neurodevelopmental outcomes. Read More
A new mouse study reveals a drug compound is effective at treating and potentially reversing symptoms of Fragile x syndrome. Read More
Mouse models with one good copy and one inactive copy of the MEF2C gene showed social deficits, hyperactivity, repetitive behaviors, and significant reductions in vocalization. Read More
