Autism

Research articles covering work related to austism spectrum disorders are provided below.

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Is it autism? The line is getting increasingly blurry

A new meta-analysis of autism data reveals the difference between people diagnosed with autism and the general population is shrinking. Measurable differences between people with ASD and people not on the spectrum has decreased over the past 50 years. Researchers say the definition of autism may be getting too blurry to be meaningful, and the condition may be at risk of being trivialized.... Read More...
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Decoding touch: Potential therapy for abnormal touch sensitivity in autism spectrum disorders

Isoguavacine, an old experimental compound which exclusively targets peripheral neurons, mitigates abnormal touch sensitivity in mouse models of ASD. The compound also improved body mass, reduces anxiety, and in one genetic subset of mice, prevented the development of brain abnormalities that arise from altered touch response.... Read More...
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Brain protein mutation from child with autism causes autism-like behavioral change in mice

Researchers implanted a genetic mutation that encodes the DAT protein from a child with ASD into mice. The mice began to exhibit autism-like behavioral deficits. Mice with the DAT T356M mutation had reduced social interaction and a loss in social dominance. The mice also demonstrated an increase in hyperactivity. At the physiological level, the researchers found impaired striatal dopamine transmission and clearance.... Read More...
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Pupil dilation and heart rate, analyzed by AI, may help spot autism early

A machine learning algorithm can accurately detect abnormalities in pupil dilation, which are predictive of ASD, in mouse models. The AI can also detect if a female has Rett syndrome with 80% accuracy. The system could be used to detect autism in infants and toddlers.... Read More...