Autism

Research articles covering work related to austism spectrum disorders are provided below.

This shows a brain

Decoding touch: Potential therapy for abnormal touch sensitivity in autism spectrum disorders

Isoguavacine, an old experimental compound which exclusively targets peripheral neurons, mitigates abnormal touch sensitivity in mouse models of ASD. The compound also improved body mass, reduces anxiety, and in one genetic subset of mice, prevented the development of brain abnormalities that arise from altered touch response.... Read More...
This shows a child looking at a DNA double helix

Brain protein mutation from child with autism causes autism-like behavioral change in mice

Researchers implanted a genetic mutation that encodes the DAT protein from a child with ASD into mice. The mice began to exhibit autism-like behavioral deficits. Mice with the DAT T356M mutation had reduced social interaction and a loss in social dominance. The mice also demonstrated an increase in hyperactivity. At the physiological level, the researchers found impaired striatal dopamine transmission and clearance.... Read More...
This shows an eye

Pupil dilation and heart rate, analyzed by AI, may help spot autism early

A machine learning algorithm can accurately detect abnormalities in pupil dilation, which are predictive of ASD, in mouse models. The AI can also detect if a female has Rett syndrome with 80% accuracy. The system could be used to detect autism in infants and toddlers.... Read More...