Autism

Research articles covering work related to austism spectrum disorders are provided below.

This shows medical files

Classification system based on co-occurring conditions may provide insight into autism

Gastrointestinal and immune disorders, along with sleep disruptions and seizures often co-occur at similar points of time in those diagnosed under the autism spectrum. Analyzing patterns in diagnosis of co-occurring medical conditions allowed for the identification of three subtypes of children with ASD. The findings could provide new insight into the mechanics of ASD.... Read More...
This shows a drawing of bacteria

Gut bacteria influence autism-like behaviors in mice

Using germ-free mouse models, researchers transplanted fecal bacteria from children on the autism spectrum and neurotypical children. Mice who received the transplants from the ASD cohort began to exhibit autism-like behaviors, whereas the mice who received transplants from typically developing children did not. Additionally, the mice showed altered gene expression in their brains and differences in types of metabolites present. In particular, the ASD mice had lower levels of 5AV and taurine. Findings suggest gut microbiota regulates autism-like behaviors via the production of neuroactive metabolites, providing further evidence for the gut-brain axis connection to the pathology of autism.... Read More...
This shows how the AI discovered the mutations

New causes of autism found in ‘junk’ DNA

Using artificial intelligence, researchers discover mutations in noncoding regions of the human genome that may result in autism. The noncoding mutations are associated with altered gene regulation in children with ASD. Additionally, the mutations affect gene expression in the brain and genes already linked to autism, such as those responsible for neuron development and migration.... Read More...