A new mouse study reveals a drug compound is effective at treating and potentially reversing symptoms of Fragile x syndrome. Read More
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Mouse models with one good copy and one inactive copy of the MEF2C gene showed social deficits, hyperactivity, repetitive behaviors, and significant reductions in vocalization. Read More
Children whose mothers had a sibling on the autism spectrum were three times as likely to be diagnosed with ASD than those whose mothers had no siblings with autism. Fathers with one or more siblings diagnosed with ASD were twice as likely to have a child diagnosed as autistic. Read More
Study points to a common gene expression profile, regardless of DNA mutations, applicable to any person on the autism spectrum. The dysregulation occurs in neural progenitor cells. While the genetic cause of ASD may be different between individuals, the behavior of the genes is similar in people with autism, and differ from those who are not on the autism spectrum. Read More
Children with autistic traits at age seven were 24% more likely to develop weekly eating disorders, including fasting, purging, and binge eating, by age 14. Read More
Maternal inflammation has been linked to a range of neurodevelopmental and psychiatric disorders in children, including autism and schizophrenia. A new mouse study reveals maternal responses and subsequent developmental disorders are based on the mother's immunoreactivity to infection. Read More
Lower levels of vasopressin were present in the cerebrospinal fluid of infants who later went on to be diagnosed with autism. Read More
Findings support the idea that lithium, a drug more commonly associated with the treatment of bipolar disorder, may help treat those with SHANK3 related autism. Read More
An over-production of eIF4E impairs microglial cells, hampering their ability to effectively prune synapses and leading to autism-like behaviors in male mouse models of ASD. Read More
Researchers identify genetic variations in the prefrontal cortex during different stages of development to assess how psychiatric conditions, such as autism and schizophrenia, may arise in individuals. Read More
Those on the autism spectrum had atypically smaller pupil dilation compared to the control group during distracting conditions while taking a push-button test. The findings suggest those with ASD may have dysregulation in locus coeruleus activity. The dysregulation of the LC may explain the exaggerated responses to environmental stimuli and fixated behaviors many with ASD experience. Read More
New findings about NLGN4 genes reveals why males are more susceptible to developing autism than females. Read More
