A new investigation into interneuron development sheds light on how disorders associated with neurodevelopment, such as autism and schizophrenia may occur.
Researchers found those on the autism spectrum with low high-density lipoprotein cholesterol or decreased ApoA1 levels had lower adaptive functioning than others with ASD.
Rare variants of the autism-associated ANK2 gene alter the architecture and organization of neurons, potentially contributing to autism and neurodevelopmental comorbidities.
Children diagnosed as being on the autism spectrum by the age of 2.5 were three times more likely to exhibit improvements in core social symptoms than those diagnosed later.
A new study suggests the differences in the gut microbiome associated with autism may be a result of restricted dietary preferences, which are a common feature of ASD, rather than a cause of autism symptoms.
Female mice exposed to PBDEs, a type of flame-retardant found on everyday household items, pass on the chemicals to their developing offspring. In female offspring, this can cause alterations in social memories and behaviors which are reminiscent of human compulsive behaviors associated with autism.
A study of genetic data from people with autism and congenital heart disease identified 23 genes associated with heart disease. 12 of the genes were previously unknown.
Researchers have identified a specific form of autism marked by the presence of an excessive amount of synapses in the cerebral cortex. The abnormality may be linked to aberrant mTOR protein activity, a regulator of synapse production.