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Autism

Research articles covering work related to austism spectrum disorders are provided below.

·August 11, 2020·4 min read

Early Neural Activity Associated With Autism

Signatures of brain activity in infants can predict autism symptoms at 18 months of age. In infants who later received a diagnosis of ASD, researchers noted decreased connectivity between frontal brain regions. The infants also showed increased connectivity across temporoparietal areas in the right hemisphere, which were associated with social information processing. Read More

Artificial Intelligence Autism Featured

·August 10, 2020·4 min read

AI-Enhanced Precision Medicine Identifies Novel Autism Subtype

Precision-medicine enhanced with the help of artificial intelligence assisted in the identification of a new autism subtype that was characterized by abnormal lipid levels. AI-enhanced precision medicine could become a biomedical screening tool for ASD. Read More

Autism Featured Open Neuroscience Articles Psychology

·August 10, 2020·5 min read

GI Symptoms Linked to Behavioral Problems in Children, Especially Those With Autism

Preschool-aged children on the autism spectrum were 2.7 times more likely to experience gastrointestinal problems, including pain, diarrhea, constipation, and vomiting than their typically developing peers. Almost 50% of those with ASD reported frequent GI symptoms, compared to 18% of those without the disorder. 30% of autistic children experienced multiple GI symptoms. Multiple GI problems were associated with sleep and attention problems, as well as self-harm, aggression, and repetitive behaviors in both children with ASD and those not on the autism spectrum. Read More

Autism Featured Neuroscience

·August 10, 2020·4 min read

Cannabis Use in Pregnancy Linked to a Greater Risk of Autism

Women who use cannabis during pregnancy are at increased risk of their child being diagnosed with autism. Read More

Autism Featured Genetics

·August 5, 2020·4 min read

How a Gene Alteration Modifies Social Behavior in Autism

Researchers have uncovered a link between the Nlgn3 gene and the oxytocin signaling pathway in mouse models of ASD. Nlgn3 disrupts the oxytocin signaling pathway in neurons in the reward system, consequentially resulting in reduced social interactions in mice. Read More

Autism Featured Open Neuroscience Articles

·August 4, 2020·4 min read

Greater Excitability in Social Brain Regions of Autistic Men Compared to Women

Males with autism have atypically enhanced excitation in the medial prefrontal cortex (mPFC). This area of the brain is associated with social cognition and self-reflection. Autistic women showed a more intact mPFC response, which was associated with a better ability to camouflage social difficulties in real-world settings. Read More

Autism Featured Neurology Open Neuroscience Articles

·July 28, 2020·5 min read

Experimental Drug for Alzheimer’s May Help Children With Autism

Children suffering from a form of autism called ADNP syndrome may benefit from an experimental drug designed to treat Alzheimer's disease. Read More

This shows the neurons mapped in the TRN

Autism Featured Neuroscience

·July 22, 2020·6 min read

Mapping the Brain’s Sensory Gatekeeper

Mapping the thalamic reticular nucleus, researchers have identified two distinct subnetworks of neurons with different functions. Findings offer insight into more specific targets for therapeutics to alleviate some sensory, sleep, and attention symptoms associated with ASD and other disorders characterized by sensory hypersensitivity. Read More

Autism Featured Neuroscience Open Neuroscience Articles

·July 14, 2020·4 min read

Autism Researchers Map Brain Circuitry of Social Preference

Study reveals how two neural circuits dictate the choice between social approach and avoidance. The network connecting the infralimbic cortex to the basolateral amygdala (BLA) impairs social behavior if there is a decrease in neural activity. Another network connecting the prelimbic cortex to the BLA similarly impairs social behavior if the neural activity is increased. Read More

Autism Featured Neuroscience

·July 13, 2020·5 min read

Vascular Development May Be At Risk in Autism

Early developmental deficits in the formation of the brain's blood vessels cause autistic traits in mouse models of ASD. Read More

This shows a child playing with building blocks

Autism Featured Neuroscience Open Neuroscience Articles

·July 7, 2020·4 min read

Sensory Neurons Outside the Brain Drive Autistic Social Behaviors

The loss of the protein neurofibromin 1 (NF1) in adult male flies resulted in social impairments. The deficits were traced back to a primary disruption in a small group of peripheral neurons which control external stimuli, including touch and smell, that communicate to the brain. Read More

Autism Featured Genetics

·June 24, 2020·4 min read

New genetic mutations linked to ASD discovered

Mutations of the CNOT1 gene affect brain development, impairing memory, and learning. The CNOT1 gene also interacts with several known autism-related genes. Read More

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