Using human stem cells to develop a brain organoid model, researchers were able to show exposure to a common pesticide synergizes with an autism-linked gene mutation. The study provides clear evidence that genetics and environment may combine to disrupt neurodevelopment.
A new gene expression study of the brains of those with autism is the largest of its kind.
Genetic mutations, which occur in both the brain and gut, could be a main cause of autism. Using mouse models of ASD, researchers discovered the neuroligin-3 R451C mutation affects neural communication in the brain and causes dysfunction in the gut. The findings strengthen the gut-brain hypothesis of autism.
Prosopagnosia, or "face-blindness", involves an entire network, not just one area of the brain. The findings may shed light on poor facial processing abilities associated with autism.
A new study sheds light on why some children with ASD also have epilepsy. Researchers report the catnap2 mutation, associated with autism, does not allow inhibitory neurons to correctly form and this can lead to an increased risk of seizures.
Findings could lead to new treatments for Rett Syndrome and other forms of autism, researchers report.
A new study aims to determine if the cannabis compound CBD can help to alleviate adverse symptoms associated with ASD.
Researchers report language and speech problems may not be the causes of the more frequent tantrums associated with autistic children.