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Genetics

Genetics articles related to neuroscience research will be listed here.

·March 22, 2023·6 min read

Multiple Substance Use Disorders May Share Inherited Genetic Signature

A common genetic signature has been linked to an increased risk of substance use disorders from smoking addiction to addiction to narcotics. The findings could pave the way to the development of new therapies for substance use disorder and may help diagnose those at risk to multiple substance use disorders.

Featured Genetics Neuroscience

·March 22, 2023·4 min read

Obesity Risk May Pass From Mothers to Daughters

Girls born to mothers with obesity may be at increased risk of becoming obese themselves, a new study reveals.

Featured Genetics Neuroscience

·March 21, 2023·5 min read

To Ward off Aging, Stem Cells Must Take Out the Trash

Blood stem cells use an unexpected method to remove misfolded proteins, and the pathway's activity declines with age. However, boosting the aggrephagy pathway could help prevent age-related diseases.

Featured Genetics Neuroscience Visual Neuroscience

·March 17, 2023·3 min read

CRISPR Gene-Editing Technique Reverses Vision Loss in Mice

Using a highly versatile form of CRISPR gene editing, researchers successfully restored vision in mice with retinitis pigmentosa.

Featured Genetics Neurology Neuroscience

·March 16, 2023·5 min read

DNA Treatment Could Delay Paralysis That Strikes Nearly All Patients With ALS

DNA designer therapeutics restored levels of a protein critical to motor neuron function, restoring the activity that is impaired as a result of ALS.

Featured Genetics Neuroscience

·March 15, 2023·3 min read

Scientists Create Baby Mice from Two Fathers

Using the genetic material from two male mice, researchers were able to successfully create baby mice. The advancement may eventually enable same-sex partners to have their own biological children.

This shows the outline of a man and a woman's head

Featured Genetics Neuroscience Psychology

·March 15, 2023·3 min read

Metabolic Disorder and Genetic Differences Associated With Female Depression

Researchers identified 11 areas of DNA that were linked to depression in women and one in males. They also found depression was associated with metabolic disease in women, providing an important new aspect to consider when treating depressive symptoms.

Featured Genetics Neuroscience Psychology

·March 13, 2023·3 min read

Novel Genes That May Increase Risk for Schizophrenia Identified

A new study has identified two novel genes associated with schizophrenia, and a third new gene linked to an increased risk of autism and schizophrenia.

Autism Featured Genetics Neuroscience

·March 10, 2023·5 min read

Could an Ancient Virus Be a Genetic Driver of Autism?

Genome and transcriptome analysis revealed BTBR autism mouse models have increased levels of endogenous retrovirus genes. BTBR/R models of ASD showed differences in the expression of a variety of genes that are indicative of endogenous retrovirus activation. BTBR/R mice exhibit autistic-like behaviors without reduced learning abilities.

Featured Genetics Neuroscience

·March 8, 2023·4 min read

How Gene Expression Controls Synaptic Plasticity in the Aging Human Brain

M1 muscarinic acetylcholine receptor (mAChR) dependent LTP and LTD share a common AMPA trafficking pathway. Either the upregulation of neurotransmitter receptor genes or suppression of the downregulation could improve synaptic dysfunction associated with age-related neurodegeneration. The findings could assist in the creation of new therapies for Alzheimer's disease that target synaptic plasticity.

Featured Genetics Neuroscience Open Neuroscience Articles

·March 8, 2023·4 min read

Modifying Messenger RNA May Provide a New Target for Alzheimer’s Disease

Targeting and reducing the methylation of a key mRNA promoted the migration of macrophages in the brain and can improve cognitive symptoms of Alzheimer's disease.

Featured Genetics Neuroscience Psychology

·March 3, 2023·3 min read

A Blood Factor Involved in Depression

In adults, levels of GDF11, a gene that is key to the regeneration of murine neural stem cells, are inversely related to depressive episodes. Administering the GDF11 proteins to aging mice reduced depressive states and improved cognition.

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