A new study sheds light on the genetic causes of a range of neurodegenerative disorders, including ALS, Parkinson's disease, and Huntington's disease, and determines factors that impact the age of onset as well as disease severity.
Rare variants of the autism-associated ANK2 gene alter the architecture and organization of neurons, potentially contributing to autism and neurodevelopmental comorbidities.
People with older-looking brains were born with lower birth weight and genes for smaller brains compared to those with normal aging brains, a new study reports. As both factors present early in life, researchers say "brain age" is likely related to early life influences and not so much on events that occur later in life.
Researchers have identified a new gene called Tango10 which plays a key role in daily circadian behavioral rhythms.
Researchers have identified a new, rare neurodevelopmental disorder associated with a homozygous mutation in the PRDM13 gene. Features of the disorder included intellectual disabilities, ataxia with cerebellar hypoplasia, and delayed puberty with hypogonadotropic hypogonadism.
The combination of bad air quality and a genetic predisposition raises the risk of a person developing depression significantly more than each factor in isolation.
Transgenic three-banded panther worms are helping researchers uncover vital clues about regeneration.
Deleting ABI3, a gene associated with Alzheimer's disease, significantly increased amyloid-beta accumulation in the brain and decreased the amount of microglia around amyloid-plaques, researchers report.
A study of genetic data from people with autism and congenital heart disease identified 23 genes associated with heart disease. 12 of the genes were previously unknown.
In both aging human and mouse experiments, researchers identified a link between the MEF2 gene and cognitive resilience. Findings suggest enhancing MEF2 activity could protect the brain against age-related dementia.