Researchers have identified a cancer-causing mutation in the PDGFRA gene that drives cell mutation and growth when activated. The findings have implications for the treatment of a subset of glioblastoma brain cancer. Read More
Microglia cells continuously survey the brain to help prevent sporadic seizures. Read More
Study provides the most complete annotated resource of proteins present in synapses to date. Read More
The inhibition of GCK-IV kinases leads to robust neuroprotection while permitting axon regeneration. The findings could lead to new treatments for neurodegenerative diseases. Read More
Researchers have identified two alternative pathways for the development of amyloid pathologies in Alzheimer's disease. Read More
A single protein called 15-PGDH appears to be a master regulator of muscle function during aging. Blocking the protein in mice increased muscle strength and endurance. Read More
A novel method detected conformational changes to the TDP-43 protein in cerebral spinal fluid associated with ALS. Read More
Focusing on gene changes as a result of epigenetic processes, such as aging, researchers were able to reverse elevated levels of harmful genes associated with memory deficits in Alzheimer's disease. Read More
Researchers have identified 216 new gene variants that appear to play a role in the development of late-onset Alzheimer's disease. Read More
SCOUT is a newly developed pipeline for clearing, labeling, 3D imaging, and analyzing cerebral organoids. Read More
Reductive stress promotes protein aggregation in neuroblastoma cells and impairs neurogenesis. Read More
Increased YTHDF3 expression appears to be a key driver in brain metastases. Read More
