Genetics

Genetics articles related to neuroscience research will be listed here.

This shows how the AI discovered the mutations

New causes of autism found in ‘junk’ DNA

Using artificial intelligence, researchers discover mutations in noncoding regions of the human genome that may result in autism. The noncoding mutations are associated with altered gene regulation in children with ASD. Additionally, the mutations affect gene expression in the brain and genes already linked to autism, such as those responsible for neuron development and migration.... Read More...
This is a diagram of the viral proteins

Coat of proteins makes viruses more infectious and links them to Alzheimer’s disease

Herpes simplex virus type 1 (HSV-1) and respiratory syncytial virus (RSV) interact with biological fluids, creating a coat of proteins around the viral surface. This results in the viruses becoming more infectious and can contribute to the formation of amyloid plaques. In animal models, researchers found these viruses can bind to amyloid proteins, which aggregate into plaques that contribute to Alzheimer's disease. HSV-1 is able to accelerate the transformation of soluble amyloid proteins into amyloid plaques.... Read More...
This shows three brains

New neurons form in the brain into tenth decade of life, even in people with Alzheimer’s

Hippocampal neurogenesis continues to occur well into old age, and in those with Alzheimer's disease. Researchers found evidence of neurogenesis in people up to the age of 99. While neurogenesis continues to occur in those with Alzheimer's disease, it is significantly reduced compared to those who have normal cognitive function.... Read More...
this is the organoid

Targeting key gene could help lead to down syndrome treatment

Using stem cells from candidates with Down syndrome to create an organoid, and employing mouse models, researchers pinpoint a gene linked to memory impairments and cognitive problems in Down syndrome. Inhibiting the OLIG2 gene leads to cognitive and memory improvements in mouse models of Down. Researchers hope their findings lead to an in utero treatment that targets the gene and helps reverse abnormal brain development. ... Read More...