Using brain organoid models, researchers have identified how the brain grows much larger and has three times as many neurons, as the brains of chimpanzees and gorillas. Read More
In the hours after death, some cells in the human brain not only remain active, they grow in size. Read More
PINK1, a gene associated with Parkinson's disease, is not just responsible for the premature death of dopaminergic neurons, it also plays a key role in the neurogenesis of dopamine neurons throughout life. Read More
Researchers found that while there are genetic overlaps between the sexes in relation to mental health disorders, there are also sex-specific differences in how genes related to the immune system, central nervous system, and blood vessels affect people with mental health problems. Read More
A new genetic engineering strategy significantly reduces levels of tau in animal models of Alzheimer's disease. The treatment, which involves a single injection, appears to have long-last effects. Read More
The LSM12-EPAC1 pathway is an important suppressor of the NCT-related pathologies associated with ALS and FTD. Read More
Researchers investigate the role the blood-brain barrier may play in age-related memory problems. Read More
A new technique which involves fusing human and chimpanzee skin cells that have been modified to act like stem cells, allowed researchers to identify two novel genetic differences between humans and chimps. Read More
Separating vascular cell data based on sex helps researchers make new discoveries about why males and females are affected by neurodegenerative diseases differently. Findings point to differences in the blood-brain barrier between males and females. Read More
Early life stress induces epigenetic modifications in D2-type medium spiny neurons in the nucleus accumbens, increasing the susceptibility to stress in adulthood. Read More
It's not only our genetics and environment that play a role in aging and longevity, it's also the random, tiny changes that arise on the cellular level. Read More
Gene activity in immune cells is altered as a result of chronic stress for women who live in areas high in violence and poverty. Read More
