Genetics

Genetics articles related to neuroscience research will be listed here.

This shows a brain

Frontotemporal dementia is associated with alterations in immune system function

Researchers discovered increased inflammatory activity in a subgroup of patients with frontotemporal dementia. The increased inflammation was indicated by elevated levels of cytokines known to increase inflammatory response and decreased levels of IL-10, which reduces inflammation. The inflammation was associated with Parkinsonism's symptoms and rapid cognitive and functional decline. The study also revealed patients with FTD are less likely to develop cancer.... Read More...
This shows a fractured outline of a head and GATC written in the background

PTSD has strong genetic component like other psychiatric disorders

Genetic data from more than 200,000 people reveals PTSD, like many other psychiatric disorders, is highly polygenic. Six loci harbor variants were strongly associated with an increased risk of PTSD. The loci hints that inflammatory and immune mechanisms may be involved in the disorder. The study also revealed a significant overlap with 21 genes implicated in depression, schizophrenia, neuroticism, insomnia, asthma, and coronary artery disease.... Read More...
This shows axons and neurons

Scientists reverse core symptom of schizophrenia in adult mice

Neuronal branches in SETD1A deficient mice are shorter and stunted. Switching off another gene, LSD1, nullifies the harmful effects of SETD1A on neuron and axon growth. After inhibiting LSD1, SETD1A deficient mice showed improved memory and axon growth. Inhibiting LSD1 not only acted on memory deficits linked to schizophrenia but also acted on the underlying molecular mechanisms associated with axonal growth. ... Read More...