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          Genetics

          Genetics articles related to neuroscience research will be listed here.

          This shows DNA and a brain
          FeaturedGeneticsNeurosciencePsychology
          ·March 13, 2023·3 min read

          Novel Genes That May Increase Risk for Schizophrenia Identified

          A new study has identified two novel genes associated with schizophrenia, and a third new gene linked to an increased risk of autism and schizophrenia.
          Read More
          This shows a brain and dna
          AutismFeaturedGeneticsNeuroscience
          ·March 10, 2023·5 min read

          Could an Ancient Virus Be a Genetic Driver of Autism?

          Genome and transcriptome analysis revealed BTBR autism mouse models have increased levels of endogenous retrovirus genes. BTBR/R models of ASD showed differences in the expression of a variety of genes that are indicative of endogenous retrovirus activation. BTBR/R mice exhibit autistic-like behaviors without reduced learning abilities.
          Read More
          This shows the outline of a head
          FeaturedGeneticsNeuroscience
          ·March 8, 2023·4 min read

          How Gene Expression Controls Synaptic Plasticity in the Aging Human Brain

          M1 muscarinic acetylcholine receptor (mAChR) dependent LTP and LTD share a common AMPA trafficking pathway. Either the upregulation of neurotransmitter receptor genes or suppression of the downregulation could improve synaptic dysfunction associated with age-related neurodegeneration. The findings could assist in the creation of new therapies for Alzheimer's disease that target synaptic plasticity.
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          This shows a brain
          FeaturedGeneticsNeuroscienceOpen Neuroscience Articles
          ·March 8, 2023·4 min read

          Modifying Messenger RNA May Provide a New Target for Alzheimer’s Disease

          Targeting and reducing the methylation of a key mRNA promoted the migration of macrophages in the brain and can improve cognitive symptoms of Alzheimer's disease.
          Read More
          This shows neural stem cells
          FeaturedGeneticsNeurosciencePsychology
          ·March 3, 2023·3 min read

          A Blood Factor Involved in Depression

          In adults, levels of GDF11, a gene that is key to the regeneration of murine neural stem cells, are inversely related to depressive episodes. Administering the GDF11 proteins to aging mice reduced depressive states and improved cognition.
          Read More
          This shows a mom and son
          FeaturedGeneticsNeuroscience
          ·March 3, 2023·4 min read

          Small Differences in Mom’s Behavior May Show Up in Child’s Epigenome

          A mother's social interaction with her child, especially if her behavior is cold or awkward, correlated with a small increase in methylation of the child's NR3C1 gene. The NR3C1 is involved in the regulation of the HPA-axis which plays a critical role in stress response and the production of cortisol.
          Read More
          This shows DNA
          FeaturedGeneticsNeuroscience
          ·March 1, 2023·3 min read

          Stress Gene Dysregulation Found in Kids After Injury From Abuse vs. Accident

          Study reports on epigenetic changes to the FKBP5 gene, a key gene associated with the regulation of stress response in the body, in babies and young children who were injured as a result of abuse, but not accidental injury.
          Read More
          This shows newly produced neurons in the dentate gyrus
          FeaturedGeneticsNeuroscienceOpen Neuroscience Articles
          ·March 1, 2023·4 min read

          How to Generate New Neurons in the Brain

          After discovering the importance of cell metabolism in neurogenesis, researchers were able to increase the number of neurons in the brains of adult and elderly mice.
          Read More
          This shows a brain
          FeaturedGeneticsNeurologyNeuroscience
          ·February 27, 2023·3 min read

          How the Brain’s Recycling System Breaks Down in Parkinson’s Disease

          Endophilin A1, a gene associated with an increased risk of Parkinson's disease also blocks the process by which the brain and body recycle waste.
          Read More
          This shows a medium spiny neuron in the nca
          FeaturedGeneticsNeuroscience
          ·February 25, 2023·6 min read

          A New Epigenetic Brain Defense Against Recurrence of Opioid Use

          HDAC5, the "epigenetics" enzyme, plays a key role in limiting opioid-associated memories and drug-seeking behaviors following abstinence from drugs in rats. The findings provide a new avenue for the treatment of opioid addiction.
          Read More
          This shows a zebrafish
          FeaturedGeneticsNeuroscienceOpen Neuroscience ArticlesPsychology
          ·February 16, 2023·5 min read

          Discovery in Zebrafish May Yield Better Understanding of a Range of Mental Health Disorders Related to Stress and Anxiety

          Deficiencies in DSCAML1 disrupt normal brain development and increase baseline levels of cortisol, making the hormone less able to function correctly during periods of stress. The findings shed new light on programmed cell death in the developing brain and could lead to new treatments for mental health disorders including stress and anxiety.
          Read More
          This shows a child playing with blocks
          AutismFeaturedGeneticsNeuroscience
          ·February 16, 2023·4 min read

          Sensory Signals Are Integrated Differently, Underrepresented by Neurons in Autism

          Environmental sensory signals are integrated differently in those with Fragile X syndrome, causing them to be underrepresented by cortical pyramidal neurons.
          Read More
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          This shows a marmoset.

          GPS of the Brain: Marmoset Gaze Reveals New Insights into Spatial Navigation

          This shows a neuron.

          BigNeuron: Revolutionizing Neuron Reconstruction with AI

          This shows a person's head.

          Vitamin D’s Crucial Role in Dopamine Function and Schizophrenia

          This shows a colorful outline of a dog's head.

          Canine Brain Atlas Sheds Light on Evolution of Human Brain Function

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