By altering the epigenetic markers on chromosomes, researchers witnessed changed gene expression in offspring and grand-offspring. The findings reveal the occurrence of transgenerational epigenetic inheritance.
New research in cloned pigs with a mutation of the SORL1 sheds light on Alzheimer's development. The findings could pave the way for new treatments for the neurodegenerative disorder.
Researchers successfully turned skin cells from Parkinson's patients into dopaminergic neurons by introducing a combination of neural-inducing genes into the skin cells.
Female mice show effects of the DAT mutation in brain regions unaffected in males, and vice versa. The findings reveal surprising differences in dopamine synapses between males and females controlling attention, pleasure, and motivation
Mice with the Alzheimer's disease-associated APOE4 and the APOE2 genes were more likely to die from COVID-19 than those with the APOE3 gene. Those with APOE4 and APOE2 genes had more virus replication in the lungs, higher inflammation, and increased tissue damage following coronavirus infection.
The TOB gene plays a significant role in reducing depression, anxiety, and fear in mouse models. The findings could have positive implications for developing new treatments for disorders associated with psychiatric stress.
Study reveals greater neuron production in the modern human frontal lobe during development compared to the Neanderthal brain. Researchers say this is due to a change in a single amino acid in the TKTL1 protein.
Stool samples taken from Viking latrines allowed researchers to map the genome of the Whipworm parasite. The study maps the parasite's global spread and relationship with human beings.