Study reveals differences in gene activity in the caudate and frontal cortex in those with ADHD.
Water plays a key role in how proteins associated with Parkinson's disease fold, clump or misfold.
The loss of the Arid1b gene interferes with brain cells implicated in signaling inhibition. Reduced inhibitory signaling has previously been associated with a range of autism-related behaviors.
Muscle weakness marked by grip strength was associated with accelerated biological aging, a new study reports.
Researchers have identified 134 genes associated with autism and a range of genetic alterations associated with ASD. Notably, the study identified changes in copy number variations with likely associations with ASD, including autism-associated variants in 14% of people on the autism spectrum.
Using monoclonal antibodies instead of conventional immunosuppressant drugs preserves stem cells in mouse brains.
Findings provide a better understanding of how natural genetic variations impact brain development and give rise to the spectrum of autism-associated behaviors.
The epigenetic clocks of those who indulged in unhealthy behaviors as teens were 1.7 to 3.3 years older than individuals who reported more healthy lifestyles as teens.
Pro-inflammatory cytokines IL-1 beta and IL-6 stimulate the expression of the schizophrenia-related C4A gene. Patients with high C4A expression displayed increased levels of IL-1 beta in cerebral spinal fluid samples. C4A levels were also correlated with markers of synaptic density. Findings reveal inflammation enhances the genetic risk variant for schizophrenia.
TRPM7 plays a role in suppressing breathing in obese mice with symptoms of sleep apnea.
A genetic form of frontotemporal dementia is associated with abnormal lipid accumulation in the brain fueled by disrupted cell metabolism. The findings could pave the way for new targeted therapies for FTD.
Intensive physical therapy in tandem with neural stem cell grafts increases tissue growth, repair, and functionality more than using the treatments alone for spinal cord injuries.
