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Genetics

Genetics articles related to neuroscience research will be listed here.

Auditory Neuroscience Featured Genetics Neuroscience

·May 27, 2023·3 min read

Gene Therapy Reverses Age-Related Hearing Loss

Researchers successfully demonstrated the efficacy of adeno-associated virus (AAV) vectors in reversing genetic hearing loss in aged animal models. The scientists developed a mature mouse model with a mutation similar to the human TMPRSS3 gene defect, which typically results in progressive hearing loss.

This shows a peron's hands and the HIV virus structure.

Featured Genetics Neuroscience

·May 25, 2023·8 min read

Stem Cell Transplants May Cure HIV

Researchers reveal two nonhuman primates were cured of Simian Immunodeficiency Virus (SIV), the monkey form of HIV, after a stem cell transplant. The team identified two circumstances that must coincide for a cure to occur and tracked the sequence in which HIV is cleared from the body. The insights may help develop a widespread cure for HIV, which affects around 38 million people globally.

Featured Genetics Neurology Neuroscience

·May 25, 2023·4 min read

RIT2 Gene’s Promise in Halting Parkinson’s Disease Progression

Researchers identified a protein that could play a significant role in preventing Parkinson's disease. The protein, linked to the RIT2 gene, is believed to control the accumulation of alpha-synuclein, which destroys neuronal cells and is a known indicator of the disease. Experiments conducted in cell models and on mice showed that increasing the expression of the RIT2 gene helped protect neurons from damage caused by alpha-synuclein.

This shows the outline of a dad, his child, and DNA.

Autism Featured Genetics Neuroscience

·May 22, 2023·3 min read

Unexpected Genetic Influence of Fathers in Autism

Researchers provide new insight into the genetic origins of Autism Spectrum Disorder (ASD). The study suggests that, contrary to long-standing beliefs, siblings with ASD may share more of their father's genome. The investigation involved analysis of over 6,000 volunteer families' genomes, revealing a potential new source of ASD.

This shows two stills of a person's head.

Featured Genetics Neuroscience Psychology

·May 21, 2023·5 min read

Shared Genetics for Cannabis Use and Psychiatric Disorders

Researchers discovered shared genetic underpinnings for cannabis use and psychiatric disorders like schizophrenia and bipolar disorder. Employing advanced statistical modelling, the study revealed a complex interplay of genetic variants increasing or decreasing risk factors for these conditions. These findings may contribute to personalized preventive measures and interventional strategies.

This shows the outline of a child's head.

Autism Featured Genetics Neuroscience

·May 19, 2023·4 min read

Potential New Treatment for a Leading Cause of Autism

Researchers have identified a potential new treatment method for Fragile X Syndrome (FXS), a leading cause of autism spectrum disorders. The method involves contracting the CGG trinucleotide repeat in the FMR1 gene, thereby restoring the essential FMRP protein expression necessary for brain development.

Featured Genetics Neuroscience

·May 19, 2023·5 min read

AI Unlocks Custom-Tailored DNA Sequences

Researchers are using artificial intelligence (AI) to dig deep into the mechanisms of gene activation, a crucial process in growth, development, and disease. Utilizing machine learning, the team identified “synthetic extreme” DNA sequences that play specific roles in gene activation. These sequences were discovered by testing millions of DNA sequences and comparing gene activation elements in humans and fruit flies.

Featured Genetics Neuroscience Psychology

·May 19, 2023·4 min read

Pivotal Protein in Female PTSD Identified

Researchers discovered an exciting new role for a widely known protein, ubiquitin, particularly in its K-63 form. They found K-63 ubiquitin selectively influences fear memory formation in female brains, potentially contributing to post-traumatic stress disorder (PTSD). This discovery sheds light on why women are more likely to suffer from PTSD and paves the way for developing female-specific therapeutic treatments.

This shows a child's head surrounded by wavy lines.

Featured Genetics Neuroscience Psychology

·May 18, 2023·5 min read

Prenatal Brain Genes Tied to Childhood Mental Illness Risk

The expression of certain genes in the brain before birth could influence the risk of developing various mental illnesses during childhood. Researchers found genetic patterns linked with adult psychiatric illnesses also correspond with psychiatric symptoms in children.

This shows the outline of a head and a brain.

Featured Genetics Neuroscience Psychology

·May 15, 2023·5 min read

Schizophrenia Risk Genes: Placenta’s Role May Outweigh Brain’s

In a paradigm shift, researchers found over 100 genes associated with schizophrenia risk operate primarily through their role in the placenta, rather than the developing brain. The research emphasizes the placenta's significance in illness development, challenging the century-old assumption that genes for schizophrenia risk primarily affect the brain.

This shows the outline of a head and DNA.

Featured Genetics Neurology Neuroscience

·May 15, 2023·10 min read

Unraveling Alzheimer’s Mystery: Rare Gene Variant Offers New Hope for Treatment

A rare gene variant that may offer protection against Alzheimer's disease has been discovered. The breakthrough came from studying a patient with a predisposition for early-onset Alzheimer's who remained cognitively healthy until his late 60s.

Featured Genetics Neuroscience

·May 10, 2023·7 min read

Global Genomic Diversity: Unveiling the New Pangenome Reference

The Human Pangenome Reference Consortium has released a comprehensive collection of human genome sequences that captures remarkable diversity across global populations. The new "pangenome" reference includes 94 distinct genome sequences from 47 individuals, with plans to increase this to 700 sequences from 350 people by mid-2024. This expanded reference will better represent the genetic diversity of the human species and help reduce health disparities in genomic analyses. It also introduces over 100 million new DNA bases, and can more accurately identify larger genomic variants.

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Genetics

Gene Therapy Reverses Age-Related Hearing Loss

Stem Cell Transplants May Cure HIV

RIT2 Gene’s Promise in Halting Parkinson’s Disease Progression

Unexpected Genetic Influence of Fathers in Autism

Shared Genetics for Cannabis Use and Psychiatric Disorders

Potential New Treatment for a Leading Cause of Autism

AI Unlocks Custom-Tailored DNA Sequences

Pivotal Protein in Female PTSD Identified

Prenatal Brain Genes Tied to Childhood Mental Illness Risk

Schizophrenia Risk Genes: Placenta’s Role May Outweigh Brain’s

Unraveling Alzheimer’s Mystery: Rare Gene Variant Offers New Hope for Treatment

Global Genomic Diversity: Unveiling the New Pangenome Reference

GPS of the Brain: Marmoset Gaze Reveals New Insights into Spatial Navigation

BigNeuron: Revolutionizing Neuron Reconstruction with AI

Vitamin D’s Crucial Role in Dopamine Function and Schizophrenia

Canine Brain Atlas Sheds Light on Evolution of Human Brain Function

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