Parkinson’s disease

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Parkinson’s disease

·June 10, 2021·6 min read

Understanding Gut Inflammation May Hold Clues to Mitigating Parkinson’s Onset

Chronic gut inflammation can trigger the clumping of alpha-synuclein in the walls of the colon, a new study reports. Researchers found chronic inflammation in the gut during early life can exacerbate the clumping of alpha-synuclein in the brains of older mice. The findings add to a growing body of evidence which links gut health to Parkinson's disease.

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·June 7, 2021·6 min read

Simple Blood Test Can Accurately Reveal Underlying Neurodegeneration

NfL, a single biomarker in the blood, can accurately predict the presence of underlying neurodegenerative disorders, such as FTD and ALS, in people with cognitive problems.

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·May 30, 2021·4 min read

Discovery May Point to Parkinson’s Disease Therapies

In Parkinson's disease, alpha-synuclein binds to LC3B. Normally, LC3B causes misfolded proteins to become degraded, but in the case of Parkinson's, LC3B becomes trapped in protein aggregates and becomes inactive.

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·May 25, 2021·4 min read

Impaired Dopamine Transporters Contribute to Parkinson’s Disease-Like Symptoms

A rare genetic mutation interferes with dopamine transporters in the brain, causing Parkinson's-like symptoms in children.

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·May 25, 2021·5 min read

Low Blood Flow in the Brain May Be an Early Sign of Parkinson’s Disease

A new study reveals a potential link between REM sleep behavior disorder and an increased risk of developing Parkinson's disease. Researchers say the sleep disorder alters cerebral blood flow, leading to a lack of oxygen in brain tissue. This, in the long term, may increase Parkinson's risk.

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·May 24, 2021·3 min read

Step-Closer to Nasal Spray Drug Delivery for Parkinson’s Disease

A new gel that contains levodopa can adhere to nasal tissue. The gel releases levodopa directly into the blood and brain. Researchers say the preliminary data reveals the gel has proven to be effective in animal models.

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·May 24, 2021·6 min read

Full-Genome CRISPR Screen Reveals Surprising Ways Neurons Survive Oxidative Stress

CRISPR gene-editing technology allowed researchers to pinpoint specific neurons and mechanisms related to the effects of oxidative stress in the brain.

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·May 19, 2021·6 min read

New Insight Into Protein Production in Brain Could Help Tackle Dementia

Researchers have identified a layer of genetic material involved in controlling the production of tau in the brain. The material is part of a larger family of non-coding genes that regulate and control other brain proteins associated with neurodegenerative disorders, such as Alzheimer's disease, Parkinson's, and PSP. The findings could lead to the development of new therapeutics to treat a range of neurodegenerative disorders.

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·May 6, 2021·3 min read

Discovery of Genetic Drivers Linked to Progression in Parkinson’s Disease

Researchers identify five genetic loci linked to the progression of Parkinson's disease.

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·May 6, 2021·5 min read

New Evidence Links Gut Bacteria and Neurodegenerative Conditions

A new study reports on an association between specific gut bacteria species and the manifestation of neurodegenerative disorders.

Featured Neurology Neuroscience

·May 4, 2021·5 min read

Brain Wave Recordings Reveal Potential For Individualized Parkinson’s Treatments

Researchers have successfully recorded brain signatures of movement symptoms and deep brain stimulation of Parkinson's patients in real time. The findings could lay the groundwork for personalize therapies for those with the neurodegenerative disease.