Volume decreases in cortical areas, the amygdala, and basal forebrain in Parkinson's patients correlated with worsening symptoms of the disease.
A new computer model shows the beneficial effects of deep brain stimulation arise from how it interrupts the cycle promoting runway beta in a circuit loop between the subthalamic nucleus and striatum.
Researchers have designed a new method of converting non-neural cells into functioning neurons that are able to form synapses, dispense dopamine, and restore the function of neurons undermined by Parkinson's associated destruction of dopaminergic cells.
A specific Parkinson's related gene could be a driver behind vocal production problems associated with the disease. The findings could lead to earlier diagnosis and treatment of Parkinson's disease.
A new deep learning algorithm utilizes neuroimaging data to differentiate between Parkinson's disease and other parkinsonian syndromes such as PSP and multiple systems atrophy.
College football players are 5 times more likely to report cognitive impairment, 2.5 times more likely to experience recurrent headaches, and 65% more likely to have cardiovascular problems in their lifetime than their non-football playing peers. Additionally, mortality from brain and other nervous system cancers was 4 times higher in former college football players than the general population.
A newly developed probiotic bacteria that can synthesize the dopamine precursor L-DOPA is safe, well-tolerated, and eliminates the side effects associated with L-DOPA use for Parkinson's disease.
Combining AI and robotics technology, researchers have identified new cellular characteristics of Parkinson's disease in skin cell samples from patients.
Older adults who take statin drugs have a lower risk of developing Parkinson's disease or parkinsonism symptoms later in life compared to those who do not take statins. Researchers speculate this may be because statins have a neuroprotective effect on arteries in the brain.