A newly developed artificial intelligence model can detect Parkinson's disease by reading a person's breathing patterns. The algorithm can also discern the severity of Parkinson's disease and track progression over time.
Those with hereditary hemochromatosis who have two copies of the gene mutation that cause the disorder have an increased risk of developing movement disorders including Parkinson's disease.
Cellular changes associated with Parkinson's disease could be revealed with the use of quantitative MRI which allows for a deeper examination of microstructures within the striatum.
Study reveals the role the VPS13C gene plays in Parkinson's disease.
Consuming seven or more units of alcohol per week is associated with increased iron levels in the brain. Higher levels of iron in the brain is linked to increased risk of neurodegenerative disorders and alcohol-related cognitive decline.
Alpha-synuclein proteins form into unusual shapes when exposed to large quantities of copper ions. Researchers say the effect of environmental copper exposure on alpha-synuclein could play a role in the pathogenesis of Parkinson's disease.
Alterations in the nascent transcription of introns may indicate risk factors for, and the progression of Parkinson's disease.
Researchers identified LIPE, a lipase that degrades triglycerides to produce fatty acids, as a potential new target for the development of treatments for Parkinson's disease.
Focusing on the largest pyramidal neurons in the motor cortex, researchers found dendritic branches do not simply pass movement information forward. Each sub-branch calculates the information and passes it to larger sub-branches, which in turn, perform the same operation. Multiple dendritic branchlets can interact with each other to amplify their combined computational product.
The Parkinson's-associated protein alpha-synuclein appears to act as a "toggle switch" that helps control vesicle transportation and gene expression. In a diseased state, this delicate balance is broken. The findings have implications for the development of new treatments for Parkinson's disease.
Older adults who frequently experience bad dreams or nightmares are twice as likely to be diagnosed with Parkinson's disease, a new study reports.
Neurons in the parafascicular thalamus project to three different parts of the basal ganglia. Targeting these circuits could be a new target for treating motor dysfunction and depression associated with Parkinson's disease.
