Two regions outside of the non-amyloid-beta-component play a critical role in controlling amyloid formation of alpha-synuclein. Read More
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The measure of iron in the brain may help doctors predict which patients with Parkinson's disease are most likely to develop dementia. Read More
Using mouse models, researchers seeded alpha-synuclein aggregates in gut neurons and discovered the clumps can travel to neurons in the brain. Read More
Ambroxol, a medication approved to treat coughs, may slow the progression of Parkinson's disease. The medication is able to effectively cross the blood-brain barrier and increases levels of GCase in patients' brains. Ambroxol also appears to reduce Parkinson's-related alpha-synuclein levels. Read More
Exposure to perfluorooctane sulfonate and perfluorooctanoic acid, so-called "forever chemicals," results in a decline of both dopamine levels and dopamine neurons in roundworms. Read More
Researchers provide new evidence of the link between Parkinson's disease and the immune system. Read More
New findings about dopaminergic neurons in the striatum could have implications for treating Parkinson's disease and Tourette syndrome. Read More
Mathematical model describes the chemical reactions responsible for the formation of Alzheimer's-linked protein. Read More
10% of patients diagnosed with Parkinson's disease are between the ages of 21 and 50. For those with young-onset Parkinson's disease, researchers report the foundations for the disease may have been apparent before they were born. The study also points to a drug, currently approved to treat precancerous skin growths, that has the potential to reduce elevated levels of alpha-synuclein. Read More
Living less than 50 meters away from a major road, or less than 150 meters away from a highway, increases the risks for dementia, Alzheimer's disease, Parkinson's disease, and multiple sclerosis. However, living close to green spaces appears to have more of a protective effect against neurodegenerative diseases. Read More
From helping to protect against certain cancers and neurodegenerative diseases to causing anxiety and insomnia, researchers investigate how coffee affects the brain, body, and overall health. Read More
Alpha synuclein's non-amyloidal component (NAC) aids the protein's movement through axons. When the NAC region is removed, alpha-synuclein did not move within axons. Read More
