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          Parkinson’s disease

          This shows a neuron.
          FeaturedNeurologyNeuroscience
          ·September 7, 2024·5 min read

          Upper GI Damage Linked to 76% Higher Parkinson’s Disease Risk

          People with a history of upper gastrointestinal (GI) damage have a 76% higher risk of developing Parkinson’s disease. The research highlights how conditions like GERD, peptic ulcers, and NSAID use may increase the risk of this neurodegenerative disorder.
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          FeaturedNeurologyNeuroscience
          ·August 8, 2024·3 min read

          Lower Dementia Risk Than Previously Thought in Parkinson’s

          A new study suggests that the risk of developing dementia in Parkinson’s disease patients may be lower or occur later than previously reported. Researchers analyzed data from two large studies, finding a 9% risk of dementia within 10 years for newly diagnosed patients and a 27% risk for those diagnosed for an average of six years. Factors increasing dementia risk included older age at diagnosis, being male, and lower education levels.
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          This shows a brain surrounded by seaweed.
          FeaturedNeurologyNeuroscience
          ·August 5, 2024·3 min read

          Seaweed Antioxidants Show Promise in Preventing Parkinson’s

          Researchers have found that antioxidants from Ecklonia cava, a type of seaweed, may help prevent Parkinson's disease by protecting dopamine-producing neurons. In mouse models, these antioxidants restored motor function and improved gut health after exposure to toxins. Cellular studies revealed that these compounds activate the AMPK enzyme and reduce harmful reactive oxygen species, potentially offering a new approach to combat neurodegeneration. This discovery highlights the potential of Ecklonia cava as a preventive ingredient against Parkinson's disease.
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          This shows stem cells.
          FeaturedGeneticsNeurologyNeuroscience
          ·July 29, 2024·5 min read

          Rapid Stem Cell Model Advances Parkinson’s Research

          Researchers have developed a model that quickly converts stem cells to brain cells with Parkinson’s disease (PD) protein structures, allowing for personalized study and treatment. This new approach can transform stem cells into brain cells within weeks, facilitating high-throughput genetic and drug screening. By mimicking diverse protein misfolding seen in PD patients, the model offers a practical tool for diagnostics and drug discovery. This advancement could lead to personalized therapies for Parkinson's and related neurodegenerative diseases.
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          This shows a neuron.
          FeaturedNeurologyNeuroscience
          ·July 16, 2024·5 min read

          AI Identifies Three Parkinson’s Subtypes

          Researchers used machine learning to identify three subtypes of Parkinson’s disease based on progression speed. These subtypes, marked by distinct genetic drivers, could enhance diagnosis and treatment strategies.
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          This shows a person with clouds around their head.
          FeaturedNeurologyNeurosciencePsychology
          ·June 25, 2024·3 min read

          Anxiety Doubles Parkinson’s Risk

          Researchers found that people over 50 with anxiety have twice the risk of developing Parkinson’s disease. Using UK primary care data from 2008-2018, the study compared 109,435 patients with anxiety to 878,256 without. Results showed increased Parkinson’s risk and identified additional risk factors like depression and sleep problems. This research suggests early detection and treatment for Parkinson’s might be possible by monitoring anxiety and related symptoms.
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          This shows blood vials.
          FeaturedNeurologyNeuroscience
          ·June 18, 2024·6 min read

          Blood Test Predicts Parkinson’s Years Before Symptoms

          Researchers have developed an AI-powered blood test that can predict Parkinson's disease up to seven years before symptoms appear. The test analyzes eight blood biomarkers and has shown 100% accuracy in diagnosing the disease. This breakthrough offers the potential for early intervention and treatment before significant damage occurs in the brain.
          Read More
          This shows bacteria.
          FeaturedGeneticsNeurologyNeuroscience
          ·June 18, 2024·5 min read

          Vitamin B Deficiency in Gut Linked to Parkinson’s

          A new study reveals a link between gut bacteria and Parkinson's disease (PD). Researchers found a decrease in genes responsible for synthesizing essential B vitamins in PD patients, which may weaken the intestinal barrier and lead to inflammation in the brain. This finding suggests that B vitamin supplementation could be a potential therapeutic avenue for PD.
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          This shows a neuron.
          Brain CancerFeaturedNeurologyNeuroscience
          ·June 17, 2024·5 min read

          Cancer Drug May Halt Parkinson’s Spread

          Researchers discovered a novel therapeutic target for Parkinson's disease, the Aplp1 protein, which facilitates the spread of harmful alpha-synuclein proteins in the brain. Notably, an FDA-approved cancer drug targeting Lag3, a protein that interacts with Aplp1, has shown promise in blocking this spread in mouse models.
          Read More
          This shows an older person.
          FeaturedNeurologyNeuroscience
          ·May 30, 2024·5 min read

          Age-Linked Sympathetic Denervation Worsens PD Non-Motor Symptoms

          Researchers found that Parkinson’s disease (PD) patients with sympathetic denervation in major salivary glands and the heart exhibit more severe non-motor symptoms as they age. This research highlights the importance of age in PD progression and could enhance the understanding of the disease's pathophysiology.
          Read More
          This shows a cup of coffee.
          FeaturedNeurologyNeuroscience
          ·May 28, 2024·4 min read

          Caffeine Intake Doesn’t Slow Parkinson’s Progression

          A new study examined the impact of caffeine on brain dopamine function in Parkinson's patients, finding no benefits on disease progression. High caffeine consumption was linked to a greater decrease in dopamine transporter binding, likely due to a compensatory mechanism rather than neuron loss.
          Read More
          This shows neurons.
          FeaturedGeneticsNeurologyNeuroscience
          ·April 30, 2024·4 min read

          Enhancing Neurogenesis for Parkinson’s Treatment

          Researchers have pioneered a method to enhance the generation of dopaminergic neurons, crucial for Parkinson’s disease treatment, by targeting specific receptors within the Wnt signaling pathway. Using synthetic antibodies, the team successfully directed stem cell differentiation in the midbrain to produce these key neurons, which are instrumental in brain health and depleted in Parkinson’s patients.
          Read More
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          How Fast Your Brain Ages Could Determine Your Future Health

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          Short Video Fosters Growth-Oriented Thinking in Adolescents

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          Can AI Truly Grasp Colorful Metaphors Without Seeing Color?

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          Mindfulness Meditation Boosts Attention Across All Ages in 30 Days

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