Latest

Parkinson’s disease

Featured Genetics Neurology Neuroscience

·November 13, 2024·6 min read

Parkinson’s Progression Linked to New Protein Pathway

Researchers have identified a protein, TMEM16F, that appears to aid the spread of Parkinson’s pathology in the brain. They found that a mutation in this protein promotes the secretion of a harmful form of α-synuclein, which moves through nerve cells, forming toxic Lewy bodies.

Featured Genetics Neurology Neuroscience

·November 3, 2024·3 min read

RNA Structures Linked to Parkinson’s Protein Aggregates

Researchers have identified unique RNA structures called G-quadruplexes (G4s) that promote harmful α-synuclein protein aggregation linked to neurodegenerative diseases like Parkinson’s. Elevated calcium levels trigger these G4s, acting as "scaffolds" for α-synuclein clumping. Administering 5-aminolevulinic acid (5-ALA) to model mice prevented aggregation and reduced motor symptoms. This breakthrough suggests that G4-targeted therapies could offer early intervention for neurodegenerative diseases.

Featured Neurology Neuroscience

·November 2, 2024·8 min read

New Blood Test Shows Promise for Early Parkinson’s Detection

Researchers have developed a method to analyze extracellular vesicles (EVs) in blood for early detection of Parkinson’s disease (PD). By isolating EVs and assessing their contents, the team identified a protein called phosphorylated α-synuclein that appears in elevated levels in PD patients.

Featured Neurology Neuroscience

·October 23, 2024·5 min read

Penicillin Use Linked to Lower Parkinson’s Risk

A new study found that people who took multiple courses of penicillin antibiotics had a 15% lower risk of developing Parkinson's disease. Researchers analyzed medical records of over 93,000 individuals and discovered a connection between gut health and the disease, suggesting that altering the gut microbiome may influence Parkinson’s risk.

Featured Genetics Neurology Neuroscience

·October 21, 2024·5 min read

Genetic Variants Linked to Brain Volume Shed Light on ADHD, Parkinson’s

A large-scale study identified 254 genetic variants that shape the volume of key brain regions responsible for memory, motor control, and behavior. Researchers analyzed DNA and brain scans from nearly 75,000 people, uncovering links between these variants and conditions like ADHD and Parkinson’s disease.

This shows a brain and a person sleeping.

Featured Neurology Neuroscience

·October 18, 2024·3 min read

REM Sleep-Inducing Neurons Identified

Researchers have discovered two neuron types in the brainstem that induce REM sleep, shedding light on the mechanisms behind this crucial sleep phase. These neurons form circuits that control brain activity, eye movement, and muscle tone loss during REM sleep.

Featured Neurology Neuroscience

·October 8, 2024·4 min read

Immune Response Linked to Lewy Body Formation

New research reveals that immune responses play a crucial role in the formation of Lewy bodies, protein aggregates that mark Parkinson's disease and other neurological conditions. Using human stem cells, scientists recreated Lewy bodies in dopaminergic neurons by combining alpha-synuclein protein buildup with immune stimulation.

Featured Neurology Neuroscience

·October 5, 2024·5 min read

New Molecule Offers Hope for Parkinson’s by Outperforming L-Dopa

A new study has discovered that ophthalmic acid, a molecule in the brain, acts like a neurotransmitter to regulate motor function, similar to dopamine. In Parkinson’s mouse models, this molecule improved movement for over 20 hours—far longer than the effects of the current treatment, L-dopa.

Featured Neuroscience Psychology Visual Neuroscience

·October 1, 2024·5 min read

Reduced Brain Response to Visual Cues Linked to Psychosis in Parkinson’s

People with Parkinson's disease (PD) who experience visual hallucinations have reduced brain responses to unexpected visual changes, a marker known as visual mismatch negativity (vMMN). Using EEG, researchers compared brain activity in PD patients with and without hallucinations and discovered that those with hallucinations showed weaker vMMN signals.

Featured Neurology Neuroscience

·September 30, 2024·5 min read

Right-Sided DBS: Effective Parkinson’s Treatment Without Speech Loss

A new study has shown that unilateral deep brain stimulation (DBS) on the right side of the brain improves motor symptoms in Parkinson's patients without causing significant declines in verbal fluency. Researchers found that DBS on the left hemisphere led to more noticeable declines in word retrieval and generation.

Featured Neurology Neuroscience

·September 27, 2024·8 min read

Improving Voice Recognition for People with Speech Disabilities

A new study shows that automatic speech recognition (ASR) systems trained on speech from people with Parkinson’s disease are 30% more accurate in transcribing similar speech patterns. Researchers collected over 151 hours of recordings from participants with varying degrees of dysarthria, a speech disorder common in Parkinson’s patients, and used the data to train ASR systems.

Featured Neurology Neuroscience

·September 27, 2024·5 min read

Metabolic Disruptions in Parkinson’s Uncover New Treatment Potential

A new study has revealed critical metabolic impairments in Parkinson’s disease (PD), focusing on purine metabolism and ATP recycling. Researchers found that patients with PD have significantly lower levels of uric acid and other purine metabolites in their blood and cerebrospinal fluid, affecting energy production in the brain.

1 … 4 5 6 7 8 … 77

Parkinson’s disease

Parkinson’s Progression Linked to New Protein Pathway

RNA Structures Linked to Parkinson’s Protein Aggregates

New Blood Test Shows Promise for Early Parkinson’s Detection

Penicillin Use Linked to Lower Parkinson’s Risk

Genetic Variants Linked to Brain Volume Shed Light on ADHD, Parkinson’s

REM Sleep-Inducing Neurons Identified

Immune Response Linked to Lewy Body Formation

New Molecule Offers Hope for Parkinson’s by Outperforming L-Dopa

Reduced Brain Response to Visual Cues Linked to Psychosis in Parkinson’s

Right-Sided DBS: Effective Parkinson’s Treatment Without Speech Loss

Improving Voice Recognition for People with Speech Disabilities

Metabolic Disruptions in Parkinson’s Uncover New Treatment Potential

Hearing Aids Linked to 23% Lower Dementia Risk in Epilepsy

Reading Is the Ultimate Cognitive Enhancer

Dual Brain-Machine Interfaces Unlock Bionic Hand Kinesthesia

Overcoming Endothelial Sorting to Cure Glioblastoma

Subscribe