Some viral infections could increase intercellular spreading of protein aggregates associated with neurodegenerative disorders, increasing the risk for developing Alzheimer's, Parkinson's, and other neurodegenerative diseases.
In the early stages of neurodegenerative diseases, microglia consume glucose to a greater extent than previously believed. The findings may serve as a new biomarker for a range of neurodegenerative disorders.
A new, improved DBS technique that targets specific subpopulations of neurons in the globus pallidus with short bursts of stimulation shows promising results as a treatment for Parkinson's disease.
Researchers highlight some of the current strategies being pursued to help restore lost function and regenerate brain areas affected by Parkinson's disease.
Drugs that increase signaling of Sonic Hedgehog (Shh) can help suppress the involuntary movements associated with dopamine replacement therapy for those with Parkinson's disease.
Two new intranasal drugs slow inflammation and stop the spread of alpha-synuclein in mouse models of Parkinson's disease. The drug also improved gait and balance in the animals. If the results are able to be replicated in humans, researchers say the drugs could be hailed as a "remarkable advance" in the treatment of Parkinson's disease.
Microglia immune cells can join together to form networks when needed, a new study reports. However, certain mutations associated with Parkinson's disease can impair this process.
Study reveals the molecular mechanisms implicated in the regulation of toxic proteins in neurodegenerative diseases like Alzheimer's and Parkinson's disease.
Study suggests seven compensation strategies to help those with Parkinson's disease improve mobility and walking problems.
A new study on aging reveals a surprising discovery about the connection between protein shape and mitochondrial health.
Study reports a significant number of people with Parkinson's disease have precise deficits when learning from instructions. Researchers say the problems are associated with differences in brain function.
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··3 min readNovel AI technology allows researchers to understand which brain regions directly interact with each other, which helps guide the placement of electrodes for DBS to treat neurological diseases.
