In mice, disruption of the growth hormone receptor gene in fat cells improved insulin sensitivity in advanced age and increased lifespan.
Overexpression of KIF11, a gene associated with the structure and function of neurons, prevents and protects against cognitive decline in both mouse models and humans with Alzheimer's disease pathologies. Boosting KIF11 expression could be beneficial in preventing cognitive decline, and boosting learning and memory in Alzheimer's patients.
Neurons derived from stem cells of combat veterans with PTSD react differently to stress hormones than those derived from veterans without PTSD. The findings shed new light on how genetics can cause some to develop PTSD following a traumatic event.
Study identifies the synaptotagmin-3 (SYT3) protein as a key molecule that allows for synaptic transmission. The findings could help with the development of treatment for a range of neurological disorders including ASD and epilepsy.
Bubonic plague, or the "Black Death" placed significantly selective pressure on humans, changing the frequency of certain immune-related genes and affecting our susceptibility to modern diseases.
Post-mortem analysis of the brains of those with Parkinson's disease revealed more than 200 genes with different epigenetic markers compared to healthy brains, but the affected genes were almost entirely different between women and men.
Some senescent (zombie) cells are embedded in young, healthy tissue and promote normal repair from damage, researchers say.
Researchers have identified risk genes for adhesive capsulitis, also known as "frozen shoulder". Carriers of these genes are at a six-fold increased risk of developing frozen shoulder.