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          Genetics

          Genetics articles related to neuroscience research will be listed here.

          This shows the outline of a head and a brain.
          FeaturedGeneticsNeurosciencePsychology
          ·May 15, 2023·5 min read

          Schizophrenia Risk Genes: Placenta’s Role May Outweigh Brain’s

          In a paradigm shift, researchers found over 100 genes associated with schizophrenia risk operate primarily through their role in the placenta, rather than the developing brain. The research emphasizes the placenta's significance in illness development, challenging the century-old assumption that genes for schizophrenia risk primarily affect the brain.
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          This shows the outline of a head and DNA.
          FeaturedGeneticsNeurologyNeuroscience
          ·May 15, 2023·10 min read

          Unraveling Alzheimer’s Mystery: Rare Gene Variant Offers New Hope for Treatment

          A rare gene variant that may offer protection against Alzheimer's disease has been discovered. The breakthrough came from studying a patient with a predisposition for early-onset Alzheimer's who remained cognitively healthy until his late 60s.
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          This shows an ai representation of dna.
          FeaturedGeneticsNeuroscience
          ·May 10, 2023·7 min read

          Global Genomic Diversity: Unveiling the New Pangenome Reference

          The Human Pangenome Reference Consortium has released a comprehensive collection of human genome sequences that captures remarkable diversity across global populations. The new "pangenome" reference includes 94 distinct genome sequences from 47 individuals, with plans to increase this to 700 sequences from 350 people by mid-2024. This expanded reference will better represent the genetic diversity of the human species and help reduce health disparities in genomic analyses. It also introduces over 100 million new DNA bases, and can more accurately identify larger genomic variants.
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          This shows DNA and a woman's head.
          FeaturedGeneticsNeurologyNeuroscience
          ·May 9, 2023·4 min read

          Mapping Dementia’s DNA: New Genetic Risk Factors Identified

          Researchers discovered new genetic risk factors for non-Alzheimer's dementia, specifically Lewy body dementia (LBD) and frontotemporal dementia (FTD). The team identified large-scale DNA changes, known as structural variants, that could increase the risk of these diseases. Notably, a previously unknown variant in the gene TCPN1 was linked to a higher risk for LBD, highlighting the significance of genetic research in combating neurodegenerative diseases.
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          This shows neurons.
          FeaturedGeneticsNeurologyNeuroscience
          ·May 9, 2023·4 min read

          Shared Genetic Defects in ALS and FTD: New Insights Into Neurodegeneration

          Some patients with ALS/motor neuron disease (MND) and frontotemporal dementia (FTD) carry the same rare genetic defects that cause other neurodegenerative diseases. These defects, known as short tandem repeat expansions, are the cause of more than 20 neurodegenerative diseases including spinocerebellar ataxias and myotonic dystrophy.
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          This shows two skulls.
          FeaturedGeneticsNeuroscience
          ·May 8, 2023·5 min read

          Neanderthal DNA Shapes Human Nose

          A specific gene inherited from Neanderthals may be responsible for the shape of our noses. The researchers found the gene contributes to nasal height and may have been inherited from the ancient human ancestor to help humans adapt to colder climates as our ancestors moved out of Africa.
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          This shows a woman wearing glasses
          FeaturedGeneticsNeuroscience
          ·May 6, 2023·4 min read

          Breaking the Darkness: Reactivating Dormant Cells in the Retina Brings New Hope for Vision Regeneration

          Researchers discovered a way to reactivate dormant cells in the retina of mice to restore vision, without the need for transplantation. The team discovered dormant glial cells can be transformed into cells sharing properties with cone photoreceptors, which enable color perception, reading and driving. The approach, which uses two genes to transform Müller cells into retinal neurons, could offer new hope for developing regenerative therapies to replace lost cells in retinal degeneration.
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          This shows a straand of dna
          FeaturedGeneticsNeuroscience
          ·April 30, 2023·6 min read

          Uncovering the Human Genome’s Secrets: 240 Mammalian Species Shed Light on What Makes Us Unique

          Researchers analyzed the DNA sequences from 240 mammalian species, showing how comparative genomics can shed light on how certain species achieve extraordinary feats and help scientists better understand the functional parts of the human genome. By identifying regions of the genomes that are most conserved across mammalian species, they pinpointed the genetic basis for uncommon mammalian traits, such as the ability to hibernate or detect faint scents from miles away. They also found genetic variants that are more likely to play causal roles in rare and common human diseases.
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          This shows dna
          FeaturedGeneticsNeurosciencePsychology
          ·April 27, 2023·5 min read

          Identification of DNA Methylation Markers in Newborns for Increased Schizophrenia Risk

          Researchers identified DNA methylation markers that may indicate the risk of developing schizophrenia later in life in newborns. This breakthrough discovery could allow for early detection and intervention to reduce the impact of the disease. By studying blood samples collected at birth, the team was able to identify unique methylation differences in cell types that could become potential clinical biomarkers for future early detection of schizophrenia.
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          This shows an eye
          FeaturedGeneticsNeuroscienceVisual Neuroscience
          ·April 26, 2023·3 min read

          Gene Therapy for Dogs With Inherited Blinding Eye Disease Set for Human Trials

          A groundbreaking gene therapy proven successful in treating an inherited, blinding eye disease in dogs is now poised for clinical trials in humans with the rare condition retinitis pigmentosa. The therapy, which halts vision loss by introducing a normal copy of the CNGB1 gene, could potentially benefit around 2 million people affected worldwide.
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          This shows a brain in a light bulb
          FeaturedGeneticsNeuroscience
          ·April 25, 2023·4 min read

          Unraveling the Genetic Mechanisms Behind Long-Lasting Memories in the Brain

          Researchers shed new light on the molecular and genetic basis of long-term memory formation in the brain. A new study reveals a single stimulation to the synapses of hippocampal neurons triggered numerous cycles where the memory-coding Arc gene produced mRNA molecules that were then translated into synapse-strengthening Arc proteins. From the findings, researchers determined a novel feedback loop that helps explain how short-lived mRNA and proteins create long-term memories in the brain.
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          This shows a brain and dna
          FeaturedGeneticsNeurosciencePsychology
          ·April 25, 2023·4 min read

          Genetic Driver of Anxiety Discovered

          An international team of scientists has identified a gene in the brain responsible for anxiety symptoms and found that modifying the gene can reduce anxiety levels, offering a novel drug target for anxiety disorders. The discovery highlights a new amygdala miR483-5p/Pgap2 pathway that regulates the brain's response to stress and provides a potential therapeutic approach for anxiety disorders.
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          This shows two women drinking.

          Empathy’s Influence on Drinking Patterns

          This shows a sleeping man.

          Sleep Apnea and Its Link to Alzheimer’s Associated Brain Changes

          This shows a woman covered in leaves.

          Getting the Skinny on Cannabis Use: The Effect of Cannabis on Weight and Metabolism

          This shows the outline of two heads made of clocks.

          Intelligence and Decision-Making: Do Smarter People Really Think Faster?

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