Microglia showed DNA methylation profiles that were distinct from other cells in the central nervous system.
The father's genes drive a fetus' demand for larger blood vessels and more nutrients, while maternal genes in the placenta try to take control over how much nourishment the mother provides.
Carriers of the Alzheimer's associated APOE4 gene have more than double the risk of developing severe COVID-19, a new study reports. Additionally, more microscopic hemorrhages were found in the brains of APOE4 carriers who contracted coronavirus. Researchers report those with the APOE4 gene also are more susceptible to developing long-term symptoms following COVID infection, including an increased risk of mental fatigue.
In fruit fly models, an ABCA1 agonist can restore specific alterations of neuroprotective mechanisms associated with a genetic predisposition to Alzheimer's disease.
Study identifies a link between how cells produce energy for brain function and a genetic mutation associated with Alzheimer's disease.
A new international clinical trial has been launched with an aim of preventing Alzheimer's disease in people with a genetic disposition who are likely to develop the disease at a younger age.
The deletion of the autism-associated Tbx1 gene results in slower cognitive processing and decreased myelin in mouse models.
Genes only play a moderate role in the accumulation of amyloid beta in the brain.
Study reveals how an enzyme called NOX4 is essential for exercise-induced reactive oxygen species and the adaptive response that drives metabolic health.
Children with autism have abnormally low levels of the CNTNAP2 protein. The protein, which can be detected in cerebrospinal fluid samples, may serve as a new biomarker for autism and could potentially become a target to treat epilepsy that is commonly associated with ASD.
Genetic differences contribute to both an increased risk of certain types of chronic pain and a reduction in the size of specific brain regions.
Findings reveal a common Parkinson's disease genetic mutation drives mislocalization of iron in activated microglia.
