Researchers developed a new method for producing high numbers of human photoreceptor cells. The human photoreceptor cells can be transplanted in bulk to partially degenerated mouse retinas and improve the detection of daylight in mice with damaged eyesight.
Study reveals the mechanism by which genes coding for a subset of long non-coding RNA interacts with neighboring genes to regulate the development and function of cortical neurons.
Infiltrating gliomas are shaped by their genetic evolution and microenvironment, researchers report. The findings may help in the development of therapies to treat glioma brain tumors.
The Parkinson's-associated protein alpha-synuclein appears to act as a "toggle switch" that helps control vesicle transportation and gene expression. In a diseased state, this delicate balance is broken. The findings have implications for the development of new treatments for Parkinson's disease.