A newly developed novel fusion protein drug efficiently eliminates amyloid beta via an entirely different mechanism than amyloid-beta antibody-based immunotherapy.
Microglia that express the Alzheimer's associated APOE4 genetic variant are unable to effectively metabolize lipids. This causes lipids to build up, promoting inflammation and preventing effective neurotransmission.
Study reveals striking similarities in both behaviors and neuroanatomical changes between people with schizophrenia and behavioral-variant frontotemporal dementia.
Study questions whether smell loss associated with COVID-19 infection may increase the risk of developing dementia later in life.
Recent scandals in Alzheimer's research and problems with medications designed to help those with Alzheimer's but failing to deliver sufficient results have researchers questioning the overwhelming focus on amyloid-beta in Alzheimer's research.
Study reveals how somatostatin and copper affect amyloid beta in Alzheimer’s disease pathology.
Varicella zoster virus (VZV), the virus that causes chickenpox and shingles, may activate the herpes simplex virus and trigger the onset of Alzheimer's disease, a new mouse study found.
Smell loss in older individuals not only can predict cognitive decline, but it can also foretell structural changes in brain structures linked to Alzheimer's disease, a new study reports.
Consuming a diet rich in ultra-processed foods like chips, cookies, deep-fried foods, and salty snacks were associated with a higher risk of developing dementia.
The study reveals that performing household chores, exercising, and social interactions significantly reduce the risk of dementia.
In cognitively healthy people with a genetic risk for Alzheimer's, retinal changes have been associated with alterations in the entorhinal cortex, hippocampus, and lingual gyrus. Researchers say retinal changes can be used to track changes in brain structures associated with Alzheimer's in those with genetic risk factors.
A person's ability to self-reflect is associated with cognition and glucose metabolism later in life, a new study finds. Those who engage in more self-reflection had improved cognition, better overall brain health, and increased glucose metabolism later in life.