New research in cloned pigs with a mutation of the SORL1 sheds light on Alzheimer's development. The findings could pave the way for new treatments for the neurodegenerative disorder.
Two new studies strengthen the link between gum disease and the development of Alzheimer's disease. The studies focus on the interactions between the gingipains enzyme interacts with the Tau protein, and how the gingipains enzyme contributes to the development of amyloid-beta.
Mice with the Alzheimer's disease-associated APOE4 and the APOE2 genes were more likely to die from COVID-19 than those with the APOE3 gene. Those with APOE4 and APOE2 genes had more virus replication in the lungs, higher inflammation, and increased tissue damage following coronavirus infection.
Middle-aged people who experience at least one nightmare a week are four times more likely to experience cognitive decline during the following decade. Older adults who experience weekly nightmares are twice as likely to develop dementia. The association is much stronger for men than women.
Rather than being simply a brain disease, researchers propose Alzheimer's disease could be a disorder of the immune system within the brain.
Getting the recommended amount of sleep, daily exercise, eating a healthy diet, and resisting alcohol and tobacco are among the seven identified lifestyle alterations those with diabetes should take to decrease their risk of developing dementia.
Early-to-midlife infections that require hospital care are associated with an increased risk of developing Alzheimer's and Parkinson's disease later in life, a new study reports.
Researchers found significant cognitive benefits for older adults who took daily multivitamin-mineral supplements.
The risk of developing Alzheimer's disease almost doubled in older people during the one-year period following COVID-19 infection.
Good dental health can help protect against cognitive decline and dementia. Tooth decay was associated with a 23% increased risk of cognitive decline and a 21% increased risk of dementia.
Study reveals a novel mechanism in locus coeruleus neurons caused by the loss of the GPT2 mitochondrial enzyme that is implicated in the development and progression of neurodegenerative diseases.