The genetic background around APOE region can modify the Alzheimer's disease-associated APOE4 risk effects.
Study reveals the role of the urea cycle in the brain and explores the dual nature of astrocytes in the brains of those with Alzheimer's pathology.
Researchers explore how diet, exercise, and social engagement can help stave off cognitive impairment and improve overall brain health.
A smaller version of the amyloid-beta protein, AB 1-40, builds up on the wall of small arteries and reduces blood flow to the brain, a new study reports.
A neuroimaging-based machine learning algorithm can detect Alzheimer's in the brain with 98% accuracy. The system is also 79% accurate at determining which stage of Alzheimer's disease a patient has.
Willingness in older people to give more money away appears to correlate with cognitive decline associated with dementia. The findings may explain why many older adults could be more prone to financial exploitation.
Researchers found an association between low vitamin D levels and reduced brain volume. Lower vitamin D was also linked to an increased risk of stroke and dementia. Up to 17% of dementia cases could be prevented by increasing vitamin D.
Adopting a healthy lifestyle or adopting minor lifestyle changes helps reduce the risks of developing Alzheimer's disease, especially for those from a lower socioeconomic background.
The prevalence of brain changes associated with LATE, a form of dementia first identified in 2019, may be as high as 40% in older adults and 50% in those with Alzheimer's disease.
People who suffer cardiometabolic disorders, such as stroke, diabetes, or a heart attack, either as stand-alone conditions or a combination of the conditions, have an increased risk of developing dementia regardless of whether or not they have a genetic predisposition for neurodegeneration.
Despite speculation that inflammation associated with the shingles virus can increase dementia risk, researchers found little evidence to substantiate the claim.
People with higher levels of omega-3 DHA in their blood are 49% less likely to develop dementia than those with lower levels. Researchers say adding additional omega-3 DHA to the diet, especially in those with the Alzheimer's associated Apoe4 gene, could slow the development and progress of dementia.