Rapamycin, a drug approved for the treatment of cancer and transplant patients increases amyloid-beta protein plaques in the brains of mice.
The heat produced by amyloid-beta aggregation may cause other, healthy amyloid-beta to aggregate, causing more and more aggregates to form. However, with the addition of a novel drug compound, amyloid-beta aggregation can be stopped and the cell temperature lowered.
Fragmented tau that accumulates in neurons in those with Alzheimer's disease may be a new target for drugs to treat the neurodegenerative disease.
A new mouse study reveals a breakdown in the process that clears brain cells of waste products precedes the buildup of amyloid plaques associated with Alzheimer's disease.
Study evaluates whether problems in facial processing and recognition in Alzheimer's disease are a result of memory impairment or visual processing deficits.
Older adults who consumed cranberries frequently as part of their diet saw improvements in episodic memory, neural function, and brain perfusion. Cranberry consumption was also linked to a significant decrease in LDL cholesterol. Findings reveal adding cranberries to the diet helps to improve memory and could protect against dementia.
Singing in a social group such as a choir may help protect cognitive function and treat aphasia in older adults.
Glycan, a special sugar protein, appears to play a significant role in the development of Alzheimer's disease.
The FMNL2 gene links cerebrovascular disease and Alzheimer's disease, a new study reports. Changes of activity in the FMNL2 caused by cerebrovascular disease prevent the efficient cleaning of toxic proteins in the brain, leading to the development of Alzheimer's disease.
From keeping active and eating a healthy diet to controlling cholesterol and reducing sugar intake, researchers report on seven simple lifestyle changes older adults with genetic risk factors can make to reduce the chance of developing dementia.