Dampening retromer activity slows down the trafficking of tau in neurodegenerative disorders, a new study reports.
Listening to music from their youth or songs with a strong emotional connection allows those with dementia to enhance social engagement and reduces neuropsychological symptoms of dementia such as anxiety, depression, and aggression. Musical intervention also sparks an emotional connection between the patient and their caregivers.
Alzheimer's disease disrupts some forms of visual memory by degrading a newly identified brain circuit that connects the primary visual cortex of each hemisphere.
Increasing neurogenesis by deleting the Bax gene in mouse models of Alzheimer's improved the animals' performance in tests measuring spatial recognition and contextual memory.
Researchers have identified multiple new risk genes for Alzheimer's disease and progressive supranuclear palsy (PSP).
DDT exposure causes sodium channels to remain open, leading to increased neural firing and an increased release of amyloid beta peptide. Blocking the channels with tetrodotoxin reduces the toxic amyloid protein by increasing the production of the amyloid precursor protein.
A1R-CT, a novel peptide that binds to neurabin, can be administered via a nasal spray and holds the potential to interrupt uncontrollable brain activity associated with TBI, stroke, epilepsy, and Alzheimer's disease.
Using CRISPR gene editing, researchers were able to control microglia and reverse their toxic state associated with Alzheimer's disease, and put them back on track.
Dementia patients with a history of cancer demonstrate better cognition at dementia diagnosis than their peers with no history of cancer.
A new collection of articles explores mapping brain overexcitability that underpins the dysregulation of vigilance, sleep-wake cycles, and validating effective biomarkers for Alzheimer's disease.
Researchers identified a pathway that begins in the gut and ends with a pro-inflammatory protein in the brain that appears to contribute to the development and progression of Alzheimer's disease.
The effects of COVID-19 infection on neurological health are becoming more apparent. A new study reveals COVID-19 can predispose people to irreversible neurological conditions, accelerate brain aging, and increase the risk of stroke and brain bleeds.
