Salt crystals can precipitate at low concentrations due to local density fluctuations. Their repeated precipitation dissolution behavior promotes amyloid-beta peptide aggregation. Read More
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Being vaccinated against influenza was associated with a 17% reduction in Alzheimer's incidence. Pneumonia vaccinations given between the ages of 65 and 75, reduced Alzheimer's risk by up to 40%. Read More
Older adults with a higher ability to process sensations, including vision, olfaction, hearing, and touch, had half the risk of being diagnosed with cognitive decline than their peers who were less capable at sensory processing tasks. Read More
Oxytocin, the so-called "love hormone," could help to treat cognitive disorders, including Alzheimer's disease. Researchers demonstrated oxytocin reversed the effects of amyloid-beta on hippocampal LTP in mice. The findings suggest oxytocin could be used as a therapeutic for the treatment of Alzheimer's disease and other dementias. Read More
APOEe4, a gene associated with Alzheimer's disease risk, doesn't appear to directly affect memory performance or brain activity in older adults without cognitive impairment. However, the gene does seem to influence brain regions and systems that older at-risk adults activate to support successful memory recall. Read More
Study identified a new class of proteins that protect synapses from being destroyed. The findings have important implications for both Alzheimer's disease and schizophrenia. Read More
People with subjectively felt memory deficits also exhibited measurable cognitive deficits that were associated with abnormalities in spinal fluid. Read More
Rotigotine, a drug that acts on dopamine transmission, improves cognitive function in patients with mild-to-moderate Alzheimer's disease. While the drug did not help improve memory, it did improve executive function in the frontal lobe and positively impacted the ability of patients to perform activities of daily living. Read More
Iron accumulation in the brain's neocortex has been linked to cognitive decline in people with Alzheimer's disease. Read More
Salbutamol, a common asthma medication, shows potential for the treatment of Alzheimer's disease. The drug is effective at reducing the accumulation of insoluble fibers of the tau protein. Read More
Humanin, a peptide encoded in mitochondria, appears to have a beneficial impact on both health and longevity in both humans and animals. Higher levels of humanin in the body are associated with longer life spans and a reduced risk of neurodegenerative disorders, like Alzheimer's disease. Read More
Elevated pulse pressure in blood traveling to the brain causes inflammation, oxidative stress, and apoptosis in the blood-brain barrier that leads to brain damage. Read More
