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Pain

Pain Neuroscience news articles cover science research about pain receptors, nociceptors, nociception, sensory neurons, somatosensory cortex, chronic pain, acute pain, nocioceptors, musculoskeletal pain, therapies, phantom limb pain and other pain research.

Featured Genetics Neurology Pain

·October 17, 2017·3 min read

‘Busybody’ Protein May Get On Your Nerves, But That’s A Good Thing

Researchers have identified a protein that is critical for pain signaling.

Image shows itch and pain sensory neurons.

Featured Neurology Neuroscience Open Neuroscience Articles Pain

·October 3, 2017·3 min read

‘Gatekeeper’ in Itching Sensation Plays No Role in Pain Transmission

Researchers reveal a neurotransmitter implicated in the itch sensation plays no role in the transmission of pain sensations.

Featured Neurology Pain

·October 18, 2017·6 min read

‘Wasabi Receptor’ for Pain Discovered in Flatworms

Discovery could pave the way for new treatments for chronic pain in humans, researchers report.

Featured Neuroscience Pain

·April 23, 2026·7 min read

25% of Chronic Pain Patients Show ADHD Traits

A study of 1,000 Japanese patients reveals that undiagnosed ADHD traits may be a hidden driver behind treatment-resistant chronic pain.

Featured Neurology Neuroscience Pain

·September 1, 2021·4 min read

A Better Understanding of Chronic Pain

Brinker-related transcription regulators play a key role in the formation of nociceptive sensation and could be a new target for pain-relieving medications.

Featured Neurology Neuroscience Pain

·June 3, 2021·4 min read

A Natural Treatment for Chronic Pain

Conolidine, a natural pain killer derived from the pinwheel flower and frequently used in Chinese medicine, interacts with a newly identified opioid receptor that regulates natural opioid peptides produced in the brain.

This is an illustration of the spinal cord with the cells

Featured Neurology Neuroscience Pain

·March 4, 2021·4 min read

A New Cell Type Implicated in Chronic Pain and Inflammation

MRC1+ macrophages are dysfunctional in animal models of neuropathic pain. Stimulating the expression of the anti-inflammatory protein CD163 reduced signs of neuroinflammation in the spinal cords of mice with neuropathic pain.

This shows a cartoon of a woman rubbing her back

Featured Neurology Neuroscience Pain

·June 8, 2022·3 min read

A New Injectable Gel May Greatly Reduce Chronic Low Back Pain

Hydrafil, an experimental injectable hydrogel appears to be safe and effective in reducing chronic lower back pain associated with degenerative disc disease.

This shows nerve growth factor receptor TrkA.

Featured Neurology Neuroscience Pain

·December 6, 2024·7 min read

A Novel Pain Signaling Complex Discovered

Researchers identified a new receptor, neuropilin-1 (NRP1), which collaborates with a known receptor to regulate pain signaling from nerve growth factor. Unlike traditional signaling receptors, NRP1 acts as a co-receptor to enhance pain signals without directly transmitting them. The study showed how blocking NRP1 or disrupting its interaction with nerve growth factor could offer novel approaches to pain treatment.

Featured Neurology Pain

·April 30, 2020·2 min read

A potential treatment for chronic pain

A newly developed peptide called Tat-P4-(C5)2 is targets and only affects nerve changes that pose a problem resulting in chronic pain. Previous studies have also shown the peptide can also reduce addiction.

Featured Neuroscience Pain Psychology

·November 10, 2023·5 min read

Aching for Accord: Pain Influences Politics

Research reveals an unusual correlation between pain sensitivity and political openness. Pain-sensitive individuals tend to endorse values and show support for politicians typically associated with the opposing political camp.