Glioblastoma brain cancer cells that are more resistant to radiation therapy have higher levels of purines. Reducing the level of purines made the cancer cells more sensitive to radiation. Read More
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Glioblastoma brain cancer originates from a pool of stem cells that can be a significant distance away from where the tumor eventually forms. Read More
Researchers have identified specific characteristics of vestibular schwannomas in children. While children have similar symptoms of the brain tumors as experienced by adults, the tumor size was typically larger in pediatric patients at the time of diagnosis. Read More
An oncogene believed to be responsible for glioblastoma brain cancer has been identified. AVIL, a gene that normally helps cells to maintain their shape and size, can shift into overdrive, causing cancer cells to form and spread. Blocking the gene's activity completely destroyed glioblastoma cancer cells in mouse models, but did not have any effect on healthy cells. The findings provide potential new treatment avenues for the deadly brain cancer. Read More
Focused ultrasound treatments show promise in the fight against glioblastoma brain cancer. Sonodynamic therapy may also help treat other difficult-to-treat cancers. Read More
Cancer itself, rather than chemotherapy alone, may contribute to the development of neuropathy some patients experience. Read More
Trifluoperazine, a dopamine receptor antagonist commonly prescribed for schizophrenia, used in combination with radiation therapy delays the growth of glioblastoma brain tumors and prolongs survival for brain cancer. Read More
Neurons and immune cells work together to promote tumor growth in neurofibromatosis type 1. Read More
Administering medulloblastoma specific CAR T cells into the cerebrospinal fluid was more effective than administering via the blood. Read More
Cannabidiol (CBD) appears to slow the growth of glioblastoma brain cancer cells in both animal and human cell lines. CBD's anti-cancer actions target mitochondria, causing them to dysfunction and release harmful reactive oxygen species. Cancer cells treated with CBD exhibited significant decreases in mitochondrial activity. Read More
Glioma patients whose tumors were hypermutated showed no significant benefit when treated with checkpoint blockers. Read More
Glioma brain tumors disrupt neural synchrony between bilateral cortical regions. The findings provide new insight into the association between seizures and tumor progression. Read More
