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          Brain Cancer

          Brain CancerFeaturedGeneticsNeurology
          ·August 29, 2012·5 min read

          Could a Cancer Drug Potentially Prevent Learning Disabilities in Some Kids?

          U-M scientists stop abnormal brain cell growth in mice with neurofibromatosis using experimental tumor drug, make new discoveries in neural stem cells.
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          Brain CancerFeaturedNeurology
          ·August 24, 2012·3 min read

          Survival Statistics Show Hard Fight When Malignant Brain Tumors Appear at Multiple Sites

          When aggressive, malignant tumors appear in more than one location in the brain, patient survival tends to be significantly shorter than when the disease starts as a single tumor, even though patients in both groups undergo virtually identical treatments, according to research at Cedars-Sinai Medical Center's Maxine Dunitz Neurosurgical Research Institute.
          Read More
          Brain CancerFeaturedGeneticsNeurology
          ·August 1, 2012·3 min read

          Researchers Discover Gene that Permanently Stops Cancer Cell Proliferation

          Researchers discovered a mutant form of Chk1 gene that when expressed in cancer cells, permanently stopped their proliferation and caused cell death without the addition of any chemotherapeutic drugs. This study illustrates an unprecedented finding, that artificially activating Chk1 alone is sufficient to kill cancer cells.
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          Brain CancerFeaturedGeneticsNeurology
          ·August 1, 2012·2 min read

          Study Suggests New Treatment Target for Deadly Brain Tumors

          “We identified a subset of brain tumor cells that are slower growing or remain at rest, and appear to be the source of cancer recurrence after standard therapy in which the drug temozolomide is given to stop the tumor’s growth,” said Dr. Luis Parada. “Current therapy targets fast-growing tumor cells but not those responsible for new tumors. To the best of our knowledge, this is the first identification of a cancer stem-like cell in a spontaneously forming tumor inside a mammal.”
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          Brain CancerFeaturedNeurology
          ·July 26, 2012·5 min read

          Study Pinpoints a Genetic Cause of Most Lethal Brain Tumor and May Lead to New Treatment

          Researchers discovered that some cases of glioblastoma, the most common and aggressive form of primary brain cancer, are caused by the fusion of two adjacent genes. The study also found that drugs that target the protein produced by this genetic aberration can dramatically slow the growth of glioblastomas in mice.
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          Brain CancerFeaturedNeurology
          ·July 24, 2012·3 min read

          New Probe Provides Vital Assist in Brain Cancer Surgery

          A new probe developed uses an innovative fluorescence-reading technology to help brain surgeons distinguish cancerous tissue from normal tissue. The probe tool, now already in use at the Cancer Center for brain surgery, may one day be used for surgeries for a variety of cancers.
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          Brain CancerFeaturedNeurology
          ·July 23, 2012·5 min read

          Genetic Mutations that Cause Common Childhood Brain Tumors Identified

          Researchers at the Stanford University School of Medicine and Lucile Packard Children’s Hospital have identified several gene mutations responsible for the most common childhood brain tumor, called medulloblastoma, adding evidence to the theory that the diagnosis is a group of genetically distinct cancers with different prognoses. These and accompanying findings are likely to lead to less toxic, better targeted treatment approaches over the next two years, the researchers said.
          Read More
          Brain CancerFeaturedGeneticsNeurology
          ·July 9, 2012·3 min read

          Pediatric Tumors Traced to Stem Cells in Developing Brain

          Scientists showed in mice that disabling a gene linked to a common pediatric tumor disorder, neurofibromatosis type 1 (NF1), made stem cells from one part of the brain proliferate rapidly. But the same genetic deficit had no effect on stem cells from another brain region.
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          AutismBrain CancerFeaturedGeneticsNeurology
          ·June 29, 2012·5 min read

          Study Finds New Gene Mutations that Lead to Enlarged Brain Size, Cancer, Autism, Epilepsy

          Researchers shed light on molecular cause of childhood’s worst conditions as first step toward developing more effective treatments.
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          Brain CancerFeaturedGeneticsNeurologyNeuroscience
          ·June 20, 2012·3 min read

          Proposed Drug May Reverse Huntington’s Disease Symptoms

          Single treatment produces long-term improvement in animal models. With a single drug treatment, researchers at the Ludwig Institute for Cancer...
          Read More
          Brain CancerFeaturedGenetics
          ·June 15, 2012·3 min read

          Genetic Markers – Hope for New Brain Tumor Treatments

          Researchers at The University of Nottingham have identified three sets of genetic markers that could potentially pave the way for...
          Read More
          Brain CancerFeaturedNeurology
          ·June 13, 2012·3 min read

          Researchers Determine Pathway for Origin of Most Common Form of Brain and Spinal Cord Tumor

          Johns Hopkins scientists hope discovery will drive drug treatments. Johns Hopkins researchers say they have discovered one of the most...
          Read More
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          A 3D digital rendering showing a developing fetal brain connected by glowing neural pathways and floating DNA strands, surrounded by subtle immune cells.

          How Severe Illness During Pregnancy Alters Fetal Brain Development

          A 3D digital illustration of a human brain side-by-side comparison, highlighting the language centers glowing brightly and equally in both a younger and older brain, while executive function areas are dimmed in the older brain.

          Aging Brains Maintain Robust Language Networks Despite Cognitive Decline

          Rejuvenation of Microglia by Youth Protein TIMP2 in the Aging Brain

          Youth Protein TIMP2 Restores Immune Function in the Aging Brain

          A multi-panel documentary photo. Left: A Black man sits alone on a locker room bench with his head down. Center: A Latino man sits withdrawn at a family kitchen table. Right: A White man looks thoughtfully at wellness pamphlets in a public waiting area. All convey isolation.

          Shame, Stigma, and Culture Prevent Male Domestic Violence Survivors From Seeking Help

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