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Genetics

·January 15, 2013·2 min read

Researchers Identify New Genetic Mutation for ALS

Researchers have identified a new genetic mutation for amyotrophic lateral sclerosis (ALS), opening the door to future targeted therapies.

Featured Neuroscience

·October 26, 2012·2 min read

Stimulating Brain Cells with Light

The work will be conducted on laboratory rats modelling Parkinson’s disease. The transplanted cells will be derived from skin from an adult human and will have been “reprogrammed” as nerve cells. The light-sensitive protein is obtained from a bacterium, which uses light to gain energy.

Featured Neurology

·October 25, 2012·3 min read

Sensory Neurons Identified as Critical to Sense of Touch

The findings in fruit fly larvae demonstrate the first known function for the sensory neurons and provide insights that could broaden the understanding of chronic pain syndromes in humans.

Featured Genetics Neurology

·October 25, 2012·4 min read

Researchers at the Doorstep of Stem Cell Therapies for MS, Other Myelin Disorders

Scientists report researchers are now on the threshold of human application of stem cell therapies for a class of neurological diseases known as myelin disorders – a long list of diseases that include conditions such as multiple sclerosis, white matter stroke, cerebral palsy, certain dementias, and rare but fatal childhood disorders called pediatric leukodystrophies.

Neurons are shown. Caption describes it well.

Brain Cancer Featured Neurology

·October 22, 2012·3 min read

Aggressive Brain Tumors Can Originate from a Range of Nervous System Cells

Scientists have long believed that glioblastoma multiforme, the most aggressive type of primary brain tumor, begins in glial cells that make up supportive tissue in the brain or in neural stem cells. Researchers found that the tumors can originate from other types of differentiated cells in the nervous system, including cortical neurons.

Featured Neurology

·October 21, 2012·5 min read

Natural Process Activating Brain’s Immune Cells Could Point Way to Repairing Damaged Brain

The brain’s key “breeder” cells secrete substances that boost the numbers and strength of critical brain-based immune cells believed to play a vital role in brain health. This finding adds a new dimension to our understanding of how resident stem cells and stem cell transplants may improve brain function.

An image of stem cells is shown. Caption describes well.

Featured Neurology

·October 19, 2012·4 min read

Scientists Pinpoint Key Player in Parkinson’s Disease Neuron Loss

Stem cell study may help to unravel how a genetic mutation leads to Parkinson's symptoms. By reprogramming skin cells from Parkinson's disease patients with a known genetic mutation, researchers identified damage to neural stem cells as a powerful player in Parkinson's disease.

Featured Genetics Neuroscience Videos

·October 11, 2012·4 min read

Engineered Flies Spill Secret of Seizures

Scientists have observed the neurological mechanism behind temperature-dependent febrile seizures by genetically engineering fruit flies to harbor a mutation analogous to one that causes epileptic seizures in people. Their new study also highlights the first use of genetic engineering to swap a human genetic disease mutation into a directly analogous gene in a fly.

An image of fly spinal cord equivalent is shown.

Featured Neuroscience

·October 11, 2012·6 min read

Novel Mechanisms Underlying Major Childhood Neuromuscular Disease Identified

A study suggests that spinal muscular atrophy (SMA), a genetic neuromuscular disease in infants and children, results primarily from motor circuit dysfunction, not motor neuron or muscle cell dysfunction, as is commonly thought. In a second study, the researchers identified the molecular pathway in SMA that leads to problems with motor function.

Featured Genetics

·October 9, 2012·2 min read

Rare Genetic Disorder Points to Molecules that May Play Role in Schizophrenia

Scientists studying a rare genetic disorder have identified a molecular pathway that may play a role in schizophrenia, according to new research. The findings may one day guide researchers to new treatment options for people with schizophrenia - a devastating disease that affects approximately 1 percent of the world's population.

Featured Neurology

·October 3, 2012·3 min read

Drug Reverses Abnormal Brain Function in Rett Syndrome Mice

in a mouse model of Rett syndrome, researchers were able to reverse abnormalities in brain activity and improve neurological function by treating animals with an FDA-approved anesthesia drug, ketamine.

Schizophrenia fMRI brain scans are shown.

Featured Genetics Psychology

·October 3, 2012·4 min read

New de novo Genetic Mutations in Schizophrenia Identified

Columbia University Medical Center (CUMC) researchers have identified dozens of new spontaneous genetic mutations that play a significant role in the development of schizophrenia, adding to the growing list of genetic variants that can contribute to the disease. The schizophrenia study was the largest and most comprehensive of its kind.

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Genetics

Researchers Identify New Genetic Mutation for ALS

Stimulating Brain Cells with Light

Sensory Neurons Identified as Critical to Sense of Touch

Researchers at the Doorstep of Stem Cell Therapies for MS, Other Myelin Disorders

Aggressive Brain Tumors Can Originate from a Range of Nervous System Cells

Natural Process Activating Brain’s Immune Cells Could Point Way to Repairing Damaged Brain

Scientists Pinpoint Key Player in Parkinson’s Disease Neuron Loss

Engineered Flies Spill Secret of Seizures

Novel Mechanisms Underlying Major Childhood Neuromuscular Disease Identified

Rare Genetic Disorder Points to Molecules that May Play Role in Schizophrenia

Drug Reverses Abnormal Brain Function in Rett Syndrome Mice

New de novo Genetic Mutations in Schizophrenia Identified

Glioblastoma’s Chaos Follows Predictable Rules

One Autism Mutation Collapses the Whole Gene Network

Why Bitter Coffee Starts to Taste So Good to Your Brain

Omega-3 DHA Eases Autism Behaviors by Calming Inflammation

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