Ceramide exposure impairs the ability for neurons to make energy by directly damaging mitochondria. Additionally, ceramides force neurons to rapidly uptake glucose in order to provide cellular energy.
Forced expression of the BP3 protein allowed obese mice to reduce their fat mass, despite having a genetic predisposition to eat all the time.
Male alcohol consumption before conception was linked to significant deficits in their offspring's brain development, specifically within the neocortex. For mothers-to-be who drink alcohol, the negative outcomes of prenatal alcohol exposure on fetal brain development can be reduced with choline supplementation.
New findings could provide additional insight into the cause of glioblastoma and provide new options for personalized therapeutic treatments.
Researchers have successfully grown a functioning 3D pituitary-like structure from embryonic stem cells.
Skin-related stem cells may be key to helping restore the myelin sheath in patients with multiple sclerosis. Using mouse models, researchers discovered melanocyte stem cells can, under the right conditions, function as cells that create myelin.
Injecting a patient's own bone marrow derived stem cells significantly improved motor function within weeks in those with spinal cord injuries.
An overabundance of NOS1AP resulted in dendrites being stunted in the developing brains of rats, new research reports.
A new study reports patients with major depressive disorder and treatment resistant depression have decreased levels of acetyl-L-carnitine in their blood. The findings could lead to new blood tests to diagnose the nature and severity of depression.
The loss of the Arid1b gene interferes with brain cells implicated in signaling inhibition. Reduced inhibitory signaling has previously been associated with a range of autism-related behaviors.
Study reveals a causal genetic link between cardio-health and coffee consumption. Those who subconsciously prefer decaffeinated coffee are more likely to be prone to the adverse effects of caffeine and have risk factors for high blood pressure.
Researchers report both physical and mental exercise can affect the learning ability of future offspring, at least in mice.
