Researchers identified differences in isoforms that control Treg cells and how that affects the body's immune system response.
Mutations in the ASD/intellectual disability genes ADNP and POGZ result in abnormal activation and overexpression of immune response genes and genes for microglia. This results in abnormal brain synaptic function, characteristic of ASD and ID.
Oxidative damage to telomeres can trigger cellular senescence. The findings could lead to the development of new therapeutics for healthy aging and to combat cancers.
Researchers reveal the critical role the p62 gene plays in the selective autophagy of tau oligomers.
Medications that block serotonin and dopamine enable the life extension effect of the FMO protein in C. elegans, even in the presence of the smell of food.
Researchers have identified a novel gene called MGMT that appears to increase Alzheimer's disease risk in women.
Study reveals a possible mechanism by which anxiolytic medications act on the brain, leading to cognitive impairment.
Stem cells in human urine have the potential to regenerate tissue.
Alterations in the nascent transcription of introns may indicate risk factors for, and the progression of Parkinson's disease.
The genetic background around APOE region can modify the Alzheimer's disease-associated APOE4 risk effects.
Researchers identified three different MINAR2 genetic mutations that were responsible for deafness in 13 people from four different families.
Maternal autoantibody–related autism spectrum disorder (MAR ASD) is marked by specific maternal antibodies that react to certain proteins in the fetal brain. Examining the plasma of expecting mothers, researchers found mothers with reactivity to one of the nine MAR ASD patterns were eight times as likely to have a child diagnosed with autism.
