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Genetics

Brain Cancer Featured Genetics Neurology

·September 4, 2012·3 min read

New Gene Variants Found to Raise Risk of Neuroblastoma and Influence Tumor Progression

Researchers have discovered two gene variants that raise the risk of the pediatric cancer neuroblastoma. This is the first study to link known cancer-related genes HACE1 and LIN28B to neuroblastoma. The study broadens understanding of how gene changes may make a child susceptible to this early childhood cancer, as well as causing a tumor to progress.

Featured Neurology Open Neuroscience Articles

·August 31, 2012·5 min read

Researchers Identify Potential New Approach for Improving Quality of Life for ALS Patients

By increasing the signaling activity of a protein called muscle skeletal receptor tyrosine-protein kinase (MuSK), researchers were able to keep nerve cells attached to muscle longer into the progression of the disease in a mouse model of ALS.

Brain Cancer Featured Genetics Neurology

·August 29, 2012·5 min read

Could a Cancer Drug Potentially Prevent Learning Disabilities in Some Kids?

U-M scientists stop abnormal brain cell growth in mice with neurofibromatosis using experimental tumor drug, make new discoveries in neural stem cells.

Featured Genetics Neuroscience

·August 24, 2012·2 min read

Astrocytes Control the Generation of New Neurons from Neural Stem Cells

Neuroscience researchers show how astrocytes control the generation of new neurons in the brain. “In the brain, astrocytes control how many new neurons are formed from neural stem cells and survive to integrate into the existing neuronal networks. Astrocytes do this by secreting specific molecules but also by much less understood direct cell-cell interactions with stem cells”, says Prof. Milos Pekny.

Autism Featured Neurology

·August 22, 2012·6 min read

Low-dose Sedative Alleviates Autistic-like Behavior in Mice with Dravet Syndrome Mutation

A low dose of the sedative clonazepam alleviated autistic-like behavior in mice with a mutation that causes Dravet syndrome in humans.

Featured Neuroscience

·August 14, 2012·5 min read

An Artificial Retina With the Capacity to Restore Normal Vision

Researchers decipher the retina's neural code for brain communication to create novel, more effective prosthetic retinal device for blindness.

Featured Genetics Neuroscience

·August 9, 2012·5 min read

Neuroscientists Find Brain Stem Cells that May Be Responsible for Higher Functions, Bigger Brains

A neuron’s fate was thought to be determined by the timing of its birth date. Neuroscientists recently showed that there is a distinct stem cell progenitor that gives rise to upper layer neurons, regardless of birth date or place.

Featured Genetics Neuroscience

·August 6, 2012·4 min read

Brain’s Stem Cells Eavesdrop to Find Out When to Act

Working with mice, Johns Hopkins researchers say they have figured out how stem cells found in a part of the brain responsible for learning, memory and mood regulation decide to remain dormant or create new brain cells. Apparently, the stem cells “listen in” on the chemical communication among nearby neurons to get an idea about what is stressing the system and when they need to act.

Featured Genetics

·August 2, 2012·3 min read

Planarians Offer A Better View of Eye Development

Planarian flatworms have come under intense study for their renowned ability to regenerate any missing body part, even as adults. But now they may take on a starring role as a model system for studying eye development and eye diseases in vertebrates, including humans.

Featured Genetics Neurology

·August 2, 2012·3 min read

Researchers Find Genetic Cause for Body Tremors

Scientists knew that mutations in the FUS gene (Fused in Sarcoma) cause amyotrophic lateral sclerosis (ALS), a disease of the nerve cells in the brain and spinal cord that control voluntary muscle movement. The researchers were successful in identifying mutations in this gene that cause Essential Tremor, and proved that the disease mechanisms for ET and ALS FUS mutations are different.

Brain Cancer Featured Genetics Neurology

·August 1, 2012·3 min read

Researchers Discover Gene that Permanently Stops Cancer Cell Proliferation

Researchers discovered a mutant form of Chk1 gene that when expressed in cancer cells, permanently stopped their proliferation and caused cell death without the addition of any chemotherapeutic drugs. This study illustrates an unprecedented finding, that artificially activating Chk1 alone is sufficient to kill cancer cells.

Brain Cancer Featured Genetics Neurology

·August 1, 2012·2 min read

Study Suggests New Treatment Target for Deadly Brain Tumors

“We identified a subset of brain tumor cells that are slower growing or remain at rest, and appear to be the source of cancer recurrence after standard therapy in which the drug temozolomide is given to stop the tumor’s growth,” said Dr. Luis Parada. “Current therapy targets fast-growing tumor cells but not those responsible for new tumors. To the best of our knowledge, this is the first identification of a cancer stem-like cell in a spontaneously forming tumor inside a mammal.”

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Genetics

New Gene Variants Found to Raise Risk of Neuroblastoma and Influence Tumor Progression

Researchers Identify Potential New Approach for Improving Quality of Life for ALS Patients

Could a Cancer Drug Potentially Prevent Learning Disabilities in Some Kids?

Astrocytes Control the Generation of New Neurons from Neural Stem Cells

Low-dose Sedative Alleviates Autistic-like Behavior in Mice with Dravet Syndrome Mutation

An Artificial Retina With the Capacity to Restore Normal Vision

Neuroscientists Find Brain Stem Cells that May Be Responsible for Higher Functions, Bigger Brains

Brain’s Stem Cells Eavesdrop to Find Out When to Act

Planarians Offer A Better View of Eye Development

Researchers Find Genetic Cause for Body Tremors

Researchers Discover Gene that Permanently Stops Cancer Cell Proliferation

Study Suggests New Treatment Target for Deadly Brain Tumors

Estrogen Exposure Shields the Aging Brain

The Acoustic Science of What Makes a Great Singer

How Octopuses Lock in Long-Term Memory Without New Proteins

Enriched Environments Rewire the Brain via Shared Synaptic Gene Networks

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