Neuroscience research articles are provided.
What is neuroscience? Neuroscience is the scientific study of nervous systems. Neuroscience can involve research from many branches of science including those involving neurology, brain science, neurobiology, psychology, computer science, artificial intelligence, statistics, prosthetics, neuroimaging, engineering, medicine, physics, mathematics, pharmacology, electrophysiology, biology, robotics and technology.
– These articles focus mainly on neurology research. – What is neurology? – Definition of neurology: a science involved in the study of the nervous systems, especially of the diseases and disorders affecting them. – Neurology research can include information involving brain research, neurological disorders, medicine, brain cancer, peripheral nervous systems, central nervous systems, nerve damage, brain tumors, seizures, neurosurgery, electrophysiology, BMI, brain injuries, paralysis and spinal cord treatments.
What is Psychology? Definition of Psychology: Psychology is the study of behavior in an individual, or group. Psychology news articles are listed below.
Artificial Intelligence articles involve programming, neural engineering, artificial neural networks, artificial life, a-life, floyds, boids, emergence, machine learning, neuralbots, neuralrobotics, computational neuroscience and more involving A.I. research.
Robotics articles will cover robotics research press releases. Robotics news from universities, labs, researchers, engineers, students, high schools, conventions, competitions and more are posted and welcome.
Genetics articles related to neuroscience research will be listed here.
Neurotechnology research articles deal with robotics, AI, deep learning, machine learning, Brain Computer Interfaces, neuroprosthetics, neural implants and more. Read the latest neurotech news articles below.
REM sleep locks in skills and experiences.
Rapid eye movement or REM sleep actively converts waking experiences into lasting memories and abilities in young brains reports a new study from Washington State University Spokane.
The finding, published in Science Advances, broadens the understanding of children’s sleep needs and calls into question the increasing use of REM-disrupting medications such as stimulants and antidepressants.
The study was funded by the National Institutes of Health.
Making experience ‘stick’
Professor of medical sciences Marcos Frank said scientists have known that infant animals spend much of their early life in REM sleep, but little was understood about the actual nuts and bolts of REM’s ability to change or recombine memories.
Providing new insights, Frank and his colleagues documented the effects of sleep on vision development in young animals. The researchers found that brain circuits change in the visual cortex as animals explore the world around them, but that REM sleep is required to make those changes “stick.”
The scientists showed that the changes are locked in by ERK, an enzyme that is activated only during REM sleep.
“REM sleep acts like the chemical developer in old-fashioned photography to make traces of experience more permanent and focused in the brain,” said Frank.
“Experience is fragile,” he said. “These traces tend to vanish without REM sleep and the brain basically forgets what it saw.”
Frank said young brains, including those of human children, go through critical periods of plasticity – or remodeling – when vision, speech, language, motor skills, social skills and other higher cognitive functions are developed.
The study suggests that during these periods, REM sleep helps growing brains adjust the strength or number of their neuronal connections to match the input they receive from their environment, he said.
REM and vision development
In the 1960s, Frank said surgeons noticed that delayed removal of congenital cataracts in children resulted in severe problems such as double vision and the inability to align the eyes.
“The visual cortex is very sensitive to information it is receiving and there are critical periods for its development,” he said. “If vision is blocked at these stages, then problems result.”
The study used a model based on that finding to determine the specific effects of REM sleep on vision development. Animals had a patch placed over one eye and their brain activity was monitored both while awake and during sleep.
While in REM sleep, the animals were awakened intermittently by gentle tapping on their enclosures. Controls were awakened during non-REM sleep.
Analyses showed that normal vision did not develop in animals experiencing a REM sleep deficit.
“Without REM sleep, permanent plastic changes to the visual cortex did not occur and the ERK enzyme did not activate,” said Frank.
Previously, the researchers had determined that ERK works by turning neuronal genes into proteins, which solidify the brain changes.
Brain dreams of its experience
Frank was surprised to also discover brain activity patterns occurring in REM sleep that were similar to those seen when the animals were awake.
“It’s as if the neurons were dreaming of their waking experience,” he said.
“This is the first time these similar events have been reported to occur in the developing brain during REM sleep,” said Frank. “Up till now, there has not been strong evidence to show that waking experience reappears during REM sleep.”
He said REM sleep may be important for the development of other parts of the brain beyond the visual cortex and its effects may continue throughout a lifetime.
Consequences for children
The study “has big implications for our understanding of sleep in children,” said Frank.
“There is a lot of data accumulating that says the amount of sleep a child gets impacts his/her ability to do well in school,” he said. “This study helps explain why this might be – and why we should be cautious about restricting sleep in our children.
“We know there are different times in a child’s development when sleep needs increase – they are very high in babies but also in adolescents when their brains are changing rapidly,” he said.
“Also, it is becoming more common for pediatricians to give compounds that affect brain activity earlier in life – not just Ritalin for attention deficit disorder, but also antidepressants and other drugs,” said Frank.
“The fact is, we have very little pre-clinical research data to tell us what these drugs are doing to developing brains in both the short and long term,” he said.
“Almost all of these compounds can potentially suppress sleep and REM sleep in particular. REM sleep is very fragile – it can be inhibited by drugs very easily,” he said.
[divider]About this neuroscience research[/divider]
Funding: The research was funded by the NIH.
Source: Marcos Frank – Washington State University Image Credit: Image is credited to NeuroscienceNews.com Original Research: Abstract for for “Rapid eye movement sleep promotes cortical plasticity in the developing brain” by Michelle C. Dumoulin Bridi, Sara J. Aton, Julie Seibt, Leslie Renouard, Tammi Coleman and Marcos G. Frank in Science Advances. Published online July 3 2015 doi:10.1126/sciadv.1500105
Rapid eye movement sleep promotes cortical plasticity in the developing brain
Rapid eye movement sleep is maximal during early life, but its function in the developing brain is unknown. We investigated the role of rapid eye movement sleep in a canonical model of developmental plasticity in vivo (ocular dominance plasticity in the cat) induced by monocular deprivation. Preventing rapid eye movement sleep after monocular deprivation reduced ocular dominance plasticity and inhibited activation of a kinase critical for this plasticity (extracellular signal–regulated kinase). Chronic single-neuron recording in freely behaving cats further revealed that cortical activity during rapid eye movement sleep resembled activity present during monocular deprivation. This corresponded to times of maximal extracellular signal–regulated kinase activation. These findings indicate that rapid eye movement sleep promotes molecular and network adaptations that consolidate waking experience in the developing brain.
“Rapid eye movement sleep promotes cortical plasticity in the developing brain” by Michelle C. Dumoulin Bridi, Sara J. Aton, Julie Seibt, Leslie Renouard, Tammi Coleman and Marcos G. Frank in Science Advances. Published online July 3 2015 doi:10.1126/sciadv.1500105
[divider]Feel free to share this neuroscience news.[/divider]