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Erk

·May 24, 2025·4 min read

Boosting Ketamine’s Antidepressant Effects to Last Two Months

Ketamine is a fast-acting antidepressant that can relieve symptoms of major depressive disorder (MDD) within hours, even in treatment-resistant cases. However, its effects typically last only a week, and frequent dosing poses risks like dissociation or addiction.

Featured Neuroscience Open Neuroscience Articles

·September 29, 2022·4 min read

Unraveling the Reward Behavior: The Mechanisms Underlying the Dopamine Signaling Pathway

The direct phosphorylation of KCNQ2 by ERK occurs through the activation of the dopamine signaling pathway in the nucleus accumbens of mice.

Featured Neuroscience

·September 26, 2022·5 min read

Long-Term Memories a Matter of Order, Not Just Repetition

The formation of long-term memory relies on intrinsic neurological learning processes and the repetition of events.

Featured Neurology

·July 20, 2020·4 min read

Oxytocin Could Be Used to Treat Cognitive Disorders Like Alzheimer’s

Oxytocin, the so-called "love hormone," could help to treat cognitive disorders, including Alzheimer's disease. Researchers demonstrated oxytocin reversed the effects of amyloid-beta on hippocampal LTP in mice. The findings suggest oxytocin could be used as a therapeutic for the treatment of Alzheimer's disease and other dementias.

This shows a tissue sample from the study

Featured Neurology Open Neuroscience Articles

·July 17, 2020·5 min read

Lesion of Doom: How a Parasitic Bacterium Induces Blood Vessel Formation to Cause Lesions

Researchers discovered a bacteria of the genus Bartonella releases a protein, which they dubbed BafA, which stimulates the production of new blood vessels that support bacterial lesions. Bartonella henselae causes cat scratch disease. The findings provide new insight into the mechanisms by which infectious bacteria can produce lesions.

This shows three computerized heads against a swirly background

Featured Neuroscience Psychology

·September 30, 2019·3 min read

Cannabis study reveals how CBD offsets the psychiatric side-effects of THC

CBD blocks the ability of THC to overstimulate the ERK pathway in the hippocampus, preventing negative side effects associated with cannabis use.

Image shows a child standing under a street lamp alone

Autism Featured Genetics Neuroscience

·September 23, 2019·4 min read

Perturbed genes regulating white blood cells linked to autism genetics and severity

Blood gene expression analysis uncovered a critical gene network that is disrupted in Autism. The disrupted gene network is related to fetal brain development and is also dysregulated in ASD cellular models. The findings provide further evidence that genetic factors influencing brain development during pregnancy are a primary cause of autism spectrum disorder.

Featured Genetics Neuroscience Psychology

·February 22, 2019·9 min read

Finding the Elusive Drinking ‘Brake’

Researchers have uncovered a mechanism in the BNST that senses the negative effects of alcohol and modulates the urge to drink. The study reports that when this mechanism doesn't function correctly, we lose the ability to recognize that we have had enough to drink.

Featured Genetics

·September 13, 2018·4 min read

Disrupting Genetic Processes Reverses Aging in Human Cells

Researchers report certain genes and pathways that regulate slicing factors play a critical role in the aging process. Disrupting these genetic processes, researchers say, could reverse signs of aging in human cells.

Featured Genetics Neuroscience Open Neuroscience Articles Psychology

·July 9, 2018·5 min read

40 Genes Associated with Aggression Identified

Researchers have identified 40 new genes they believe are related to aggressive behavior in both humans and mice. The findings deepen understanding of the genetic basis of aggressiveness.

Featured Neurology

·May 23, 2018·4 min read

Myelin Boosts Neuron Growth in Spinal Cord Injuries

A new study challenges conventional belief that myelin can inhibit neuronal growth. Researchers report rat myelin stimulated axon outgrowths in neural precursor cells, and human iPSCs.

Featured Genetics Neuroscience

·April 27, 2018·5 min read

The Written History of a Neuron

Researchers report neurons record their activity in gene expression, and the activity record can be reconstructed by analyzing gene expression patterns.

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