The direct phosphorylation of KCNQ2 by ERK occurs through the activation of the dopamine signaling pathway in the nucleus accumbens of mice.
The formation of long-term memory relies on intrinsic neurological learning processes and the repetition of events.
Oxytocin, the so-called "love hormone," could help to treat cognitive disorders, including Alzheimer's disease. Researchers demonstrated oxytocin reversed the effects of amyloid-beta on hippocampal LTP in mice. The findings suggest oxytocin could be used as a therapeutic for the treatment of Alzheimer's disease and other dementias.
Researchers discovered a bacteria of the genus Bartonella releases a protein, which they dubbed BafA, which stimulates the production of new blood vessels that support bacterial lesions. Bartonella henselae causes cat scratch disease. The findings provide new insight into the mechanisms by which infectious bacteria can produce lesions.
CBD blocks the ability of THC to overstimulate the ERK pathway in the hippocampus, preventing negative side effects associated with cannabis use.
Blood gene expression analysis uncovered a critical gene network that is disrupted in Autism. The disrupted gene network is related to fetal brain development and is also dysregulated in ASD cellular models. The findings provide further evidence that genetic factors influencing brain development during pregnancy are a primary cause of autism spectrum disorder.
Researchers have uncovered a mechanism in the BNST that senses the negative effects of alcohol and modulates the urge to drink. The study reports that when this mechanism doesn't function correctly, we lose the ability to recognize that we have had enough to drink.
Researchers report certain genes and pathways that regulate slicing factors play a critical role in the aging process. Disrupting these genetic processes, researchers say, could reverse signs of aging in human cells.
Researchers have identified 40 new genes they believe are related to aggressive behavior in both humans and mice. The findings deepen understanding of the genetic basis of aggressiveness.
A new study challenges conventional belief that myelin can inhibit neuronal growth. Researchers report rat myelin stimulated axon outgrowths in neural precursor cells, and human iPSCs.
A new study reveals differences in ear function can lead to asymmetrical brain differences in mice.