antidepressants

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Common antidepressants interact with opioid med to lessen pain relief

SSRI antidepressants, such as Prozac and Paxil, interact with opioid medications to make them less effective at providing relief from chronic pain. Tramadol relies on activation of the CYP2D6 enzyme to control pain, but SSRIs inhibit this enzyme. Researchers suggest prescribing different classes of antidepressants which do not suppress the enzyme may benefit those in need of opioid medications. Alternatively, non-opioid pain killers should be considered for those who can not switch from SSRIs.... Read More...
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Commonly prescribed drugs could increase the risk of dementia

Anticholinergic drugs, commonly prescribed to treat a range of disorders, from Parkinson's disease to bladder conditions, may increase dementia risks. The increased risk was linked to anticholinergic antidepressants, antipsychotics, bladder control, epilepsy and Parkinson's disease medications. There were no increased risks associated with other types of anticholinergics, such as gastrointestinal drugs or antihistamines. ... Read More...
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Antidepressants could be used to treat multiple bacterial infections

FIASMA antidepressants, such as amitriptyline and desipramine, halt the growth of four different kinds of bacterial pathogens in cell cultures and animal models. The antidepressants have shown to be effective in killing intracellular bacteria in two chlamydia infections, as well as human granulocytic anaplasmosis, a tick-borne disease that attacks white blood cells.... Read More...