A new study reports on the importance of REM sleep for the developing brain and questions the increasing use of REM disrupting medications in children.
A new depression model is better able to predict whether a patient will respond to a specific antidepressant than seasoned psychiatrists are able to.
Researchers identify a molecular pathway which accelerates the time taken for antidepressants to work in mouse models.
While it is well-known antidepressants are effective at treating those with depression, a new study reports the medications may be beneficial as a preventative measure for those with a risk factor for depressive disorders.
A synthetic compound, decynium-22, is able to turn off SERT in the brain, enhancing the effectiveness of SSRIs.
A new study clarifies the mechanism behind how ketamine works as an antidepressant. Researchers say there is evidence to suggest ketamine binds to NMDA receptors, instead of opioid receptors. Reducing the belief that ketamine is an opioid may make patients with depression more open to using the treatment.
Researchers report ketamine's antidepressive effects require activation of opioid receptors in the brain. The study highlights the interaction between depression, pain and opioid addiction.
A new study reports sex hormones taken by those undergoing gender reassignment can alter brain chemistry and increase risk for mood disorders, especially in men transitioning into women.
Findings reveal it is possible to predict the risk of a person with MDD lapsing back into depression after stopping antidepressants. Those who relapse take longer to decide how much effort to invest for a reward.
Ketamine increases the number of serotonin 1B receptors. Ketamine binds to serotonin 1B receptors, reducing the release of serotonin and increasing the release of dopamine.
When autoantibodies are able to enter the bran and act on NMDA receptors, people experience relief from symptoms of anxiety, depression, and stress.
Researchers are embarking on a new project to develop more effective treatments for depression.
