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          antidepressants

          This shows a brain.
          FeaturedNeurosciencePsychology
          ·April 23, 2025·6 min read

          Can Brain Scans Tell Which Antidepressant Will Work for You?

          A new study shows that brain connectivity patterns, especially in the dorsal anterior cingulate cortex, can help predict how patients with major depressive disorder (MDD) will respond to antidepressants. By combining brain imaging with clinical data, researchers developed machine learning models that accurately predicted treatment outcomes across two large trials.
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          This shows a woman and mushrooms.
          FeaturedNeurosciencePsychology
          ·April 4, 2025·3 min read

          How Psilocybin Lifts Mood Without the Hallucinogenic Trip

          Researchers have uncovered two key brain mechanisms—specific neurons and a serotonin receptor—that help explain how psilocybin produces long-lasting antidepressant effects. Their study identified pyramidal tract neurons in the medial frontal cortex and the serotonin 5-HT2A receptor as essential to the therapeutic action of psilocybin.
          Read More
          This shows a brain.
          FeaturedNeurosciencePsychology
          ·February 25, 2025·3 min read

          SSRIs May Speed Up Cognitive Decline

          A new study based on data from 18,740 dementia patients suggests that antidepressants may accelerate cognitive decline. Researchers found that patients taking antidepressants, particularly SSRIs like escitalopram, citalopram, and sertraline, experienced faster deterioration compared to those not on medication.
          Read More
          This shows a brain.
          FeaturedNeurosciencePsychology
          ·February 14, 2025·4 min read

          How Ketamine Binds to Brain Receptors to Alter Mood

          New research sheds light on how ketamine affects the brain by targeting a specific NMDA receptor subtype, GluN1-2B-2D. Scientists used electron cryo-microscopy to capture how ketamine binds to this receptor, revealing multiple attachment sites that influence brain activity.
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          This shows a brain.
          FeaturedNeurosciencePsychology
          ·February 14, 2025·6 min read

          Prozac Shows Promise in Fighting Infections & Sepsis

          New research suggests that fluoxetine, commonly used as an antidepressant, may also help protect against infections and sepsis. Scientists found that the drug has antimicrobial properties and helps regulate the immune response, reducing the risk of tissue and organ damage.
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          This shows the outline of a man.
          FeaturedNeurosciencePsychology
          ·December 12, 2024·8 min read

          Gut Serotonin Plays Role in Depression and Mood

          Serotonin in the gut epithelium plays a critical role in modulating mood and may provide a safer target for treating depression and anxiety. In animal studies, increasing gut serotonin improved mood symptoms without causing digestive issues, unlike systemic antidepressant treatments.
          Read More
          This shows a brain.
          Brain CancerFeaturedNeurologyNeuroscience
          ·September 22, 2024·5 min read

          Antidepressant May Help Fight Glioblastoma Brain Tumors

          Researchers have discovered that the antidepressant vortioxetine effectively combats glioblastoma, a deadly brain tumor, in lab tests and in mice. This drug, already FDA-approved, crosses the blood-brain barrier and could potentially improve treatment for glioblastoma patients when combined with standard therapy.
          Read More
          This shows a head and psychedelic swirls.
          FeaturedNeurosciencePsychology
          ·September 22, 2024·7 min read

          Psilocybin Shows Greater Long-Term Benefits Over SSRI for Depression

          A study comparing psilocybin to the SSRI escitalopram found both drugs improved depressive symptoms similarly over six months, but psilocybin offered additional psychosocial benefits. Patients taking psilocybin reported a greater sense of meaning, psychological connectedness, and improved social functioning. These results suggest psilocybin could provide a more holistic treatment option for depression, addressing both symptoms and overall well-being. While promising, psilocybin remains experimental and is only administered in controlled environments.
          Read More
          This shows a depressed woman and pills.
          FeaturedNeurosciencePsychology
          ·June 6, 2024·8 min read

          1 in 6 Antidepressant Users Face Withdrawal Symptoms

          15% of people stopping antidepressants experience withdrawal symptoms like dizziness and nausea, while 3% face severe symptoms. The research highlights the need for careful management and counseling by healthcare professionals when discontinuing antidepressants. This study aims to provide a balanced view on the real prevalence of withdrawal symptoms and their impact.
          Read More
          This shows a depressed woman.
          FeaturedNeurosciencePsychology
          ·June 6, 2024·4 min read

          How Antidepressants Treat Major Depression

          Researchers have developed a new framework explaining how antidepressants, like SSRIs, treat major depressive disorder (MDD) by restoring brain connectivity rather than correcting a serotonin imbalance. Their findings emphasize the continued importance of these medications despite shifting public opinion. This new understanding could improve patient-clinician conversations about depression treatment.
          Read More
          This shows a head and pills.
          FeaturedNeurosciencePsychology
          ·May 30, 2024·6 min read

          AI Tool Matches Patients to Effective Antidepressants Faster

          Researchers developed an AI-based tool, MeAgainMeds.com, to help match patients with the most effective antidepressants based on their medical history. This free website aims to reduce the trial-and-error process in finding the right medication, improving patient outcomes.
          Read More
          This shows a head and pills.
          FeaturedNeurosciencePsychology
          ·May 8, 2024·5 min read

          Psychedelics Activate Serotonin to Produce Antidepressant Effect

          A new study advanced our understanding of how psychedelic drugs activate serotonin receptors to offer potential treatments for neuropsychiatric disorders. The identifies the interaction of psychedelics like LSD and psilocybin with the serotonin receptor 5-HT1A, which is pivotal in their therapeutic effects.
          Read More
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          This shows the outline of a person and the gut-bran axis.

          AI Identifies Appendix Removal and Diet as Alzheimer’s Risks

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          Heartbeat Rhythms Unveil Hidden Brain Activity

          This shows the outline of a head and DNA.

          Midlife Hobbies Outperform Genetic Alzheimer’s Risk

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          Redefining Neuroplasticity Through Selective Deactivation

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