The biological changes that occur as a result of aging could be a mechanism behind why older adults with depression do not have a full resolution of symptoms following taking antidepressants.
Researchers critique the latest findings on serotonin's role in depression and report people should maintain their current therapies to help control their symptoms of depression.
Researchers explain why the serotonin hypothesis for depression may not be as accurate as previously believed.
Study reveals how reduced function of the rgs2 protein in the nucleus accumbens contributes to symptoms associated with depression. The findings may assist with the development of new therapeutics to help treat depression in individuals.
Researchers say pharmacogenomics can assist providers in determining the best antidepressant treatments for patients with depression and avoid prescribing medications that could have adverse effects.
Ketamine's antidepressant effect is a result of the enhancement of Kcnq2 potassium channels in a certain subtype of glutamate-sensitive neurons.
Researchers explore the effect psychedelics have on the brain and how they are effective at treating depression.
Overall, people who used antidepressants to manage depression long-term did not have a better quality of physical or mental health than those with depression who did not use prescription medication to manage their symptoms.
A person's socioeconomic background may impact how well they respond to treatments for depression. Depressed people without a college degree had 9.8% less improvement in symptoms following treatment compared to graduates, and those who were unemployed had 6.6% less improvement than those with a steady job.